A Novel In Vitro Culture Model System to Study Merkel Cell Polyomavirus–Associated MCC Using Three-Dimensional Organotypic Raft Equivalents of Human Skin

Merkel cell polyomavirus (MCPyV) is a human polyomavirus causally linked to the development of Merkel cell carcinoma (MCC), an aggressive malignancy that largely arises within the dermis of the skin. In this study, we recapitulate the histopathology of human MCC tumors in vitro using an organotypic...

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Detalles Bibliográficos
Autores principales: Loke, Amanda S. W., Longley, B. Jack, Lambert, Paul F., Spurgeon, Megan E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7835998/
https://www.ncbi.nlm.nih.gov/pubmed/33478104
http://dx.doi.org/10.3390/v13010138

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