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Identification of a Dexamethasone Mediated Radioprotection Mechanism Reveals New Therapeutic Vulnerabilities in Glioblastoma

SIMPLE SUMMARY: The standard of care for patients with newly diagnosed glioblastoma (GBM) comprises surgery followed by radio- and chemotherapy. In addition, dexamethasone is used to manage the development of inflammation within the brain in general, and particularly during treatment. The effects of...

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Detalles Bibliográficos
Autores principales: Aldaz, Paula, Auzmendi-Iriarte, Jaione, Durántez, Maika, Lasheras-Otero, Irene, Carrasco-Garcia, Estefania, Zelaya, M. Victoria, Bragado, Laura, Olías-Arjona, Ana, Egaña, Larraitz, Samprón, Nicolás, Morilla, Idoia, Redondo-Muñoz, Marta, Rico, Mikel, Squatrito, Massimo, Maria-Alonso, Marta, Fernández-Irigoyen, Joaquín, Santamaria, Enrique, Larráyoz, Iñaki M., Wellbrock, Claudia, Matheu, Ander, Arozarena, Imanol
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7836009/
https://www.ncbi.nlm.nih.gov/pubmed/33478100
http://dx.doi.org/10.3390/cancers13020361