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Homocysteine Impairs Endothelial Cell Barrier Function and Angiogenic Potential via the Progranulin/EphA2 Pathway

Hyperhomocysteinemia is a well-recognized independent risk factor for cardiovascular disease. To date, the mechanism of pathological plasma homocysteine (Hcy) level elevation remains to be elucidated. We aimed to investigate the levels of progranulin (PGRN), Eph-receptor tyrosine kinase-type A2 (Eph...

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Detalles Bibliográficos
Autores principales:	Tian, Dan, Qin, Qing, Li, Mingfei, Li, Xiaoyu, Xu, Qing, Lv, Qianzhou
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7836014/ https://www.ncbi.nlm.nih.gov/pubmed/33510642 http://dx.doi.org/10.3389/fphar.2020.614760

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