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Electrophysiological and Imaging Calcium Biomarkers of Aging in Male and Female 5×FAD Mice

BACKGROUND: In animal models and tissue preparations, calcium dyshomeostasis is a biomarker of aging and Alzheimer’s disease that is associated with synaptic dysfunction, neuritic pruning, and dysregulated cellular processes. It is unclear, however, whether the onset of calcium dysregulation precede...

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Detalles Bibliográficos
Autores principales:	Ghoweri, Adam O., Ouillette, Lara, Frazier, Hilaree N., Anderson, Katie L., Lin, Ruei-Lung, Gant, John C., Parent, Rachel, Moore, Shannon, Murphy, Geoffrey G., Thibault, Olivier
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	IOS Press 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7836067/ https://www.ncbi.nlm.nih.gov/pubmed/33164928 http://dx.doi.org/10.3233/JAD-200109

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