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Temporal dynamics of SARS-CoV-2 mutation accumulation within and across infected hosts

Analysis of SARS-CoV-2 genetic diversity within infected hosts can provide insight into the generation and spread of new viral variants and may enable high resolution inference of transmission chains. However, little is known about temporal aspects of SARS-CoV-2 intrahost diversity and the extent to...

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Detalles Bibliográficos
Autores principales: Valesano, Andrew L., Rumfelt, Kalee E., Dimcheff, Derek E., Blair, Christopher N., Fitzsimmons, William J., Petrie, Joshua G., Martin, Emily T., Lauring, Adam S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7836113/
https://www.ncbi.nlm.nih.gov/pubmed/33501443
http://dx.doi.org/10.1101/2021.01.19.427330