The impacts of COVID-19 vaccine timing, number of doses, and risk prioritization on mortality in the US

As COVID-19 vaccination begins worldwide, policymakers face critical trade-offs. Using a mathematical model of COVID-19 transmission, we find that timing of the rollout is expected to have a substantially greater impact on mortality than risk-based prioritization and uptake and that prioritizing fir...

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Autores principales: Wang, Xutong, Du, Zhanwei, Johnson, Kaitlyn E., Pasco, Remy F., Fox, Spencer J., Lachmann, Michael, McLellan, Jason S., Meyers, Lauren Ancel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7836125/
https://www.ncbi.nlm.nih.gov/pubmed/33501453
http://dx.doi.org/10.1101/2021.01.18.21250071
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author Wang, Xutong
Du, Zhanwei
Johnson, Kaitlyn E.
Pasco, Remy F.
Fox, Spencer J.
Lachmann, Michael
McLellan, Jason S.
Meyers, Lauren Ancel
author_facet Wang, Xutong
Du, Zhanwei
Johnson, Kaitlyn E.
Pasco, Remy F.
Fox, Spencer J.
Lachmann, Michael
McLellan, Jason S.
Meyers, Lauren Ancel
author_sort Wang, Xutong
collection PubMed
description As COVID-19 vaccination begins worldwide, policymakers face critical trade-offs. Using a mathematical model of COVID-19 transmission, we find that timing of the rollout is expected to have a substantially greater impact on mortality than risk-based prioritization and uptake and that prioritizing first doses over second doses may be life saving.
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spelling pubmed-78361252021-01-27 The impacts of COVID-19 vaccine timing, number of doses, and risk prioritization on mortality in the US Wang, Xutong Du, Zhanwei Johnson, Kaitlyn E. Pasco, Remy F. Fox, Spencer J. Lachmann, Michael McLellan, Jason S. Meyers, Lauren Ancel medRxiv Article As COVID-19 vaccination begins worldwide, policymakers face critical trade-offs. Using a mathematical model of COVID-19 transmission, we find that timing of the rollout is expected to have a substantially greater impact on mortality than risk-based prioritization and uptake and that prioritizing first doses over second doses may be life saving. Cold Spring Harbor Laboratory 2021-02-18 /pmc/articles/PMC7836125/ /pubmed/33501453 http://dx.doi.org/10.1101/2021.01.18.21250071 Text en https://creativecommons.org/licenses/by-nc/4.0/This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License (https://creativecommons.org/licenses/by-nc/4.0/) , which allows reusers to distribute, remix, adapt, and build upon the material in any medium or format for noncommercial purposes only, and only so long as attribution is given to the creator.
spellingShingle Article
Wang, Xutong
Du, Zhanwei
Johnson, Kaitlyn E.
Pasco, Remy F.
Fox, Spencer J.
Lachmann, Michael
McLellan, Jason S.
Meyers, Lauren Ancel
The impacts of COVID-19 vaccine timing, number of doses, and risk prioritization on mortality in the US
title The impacts of COVID-19 vaccine timing, number of doses, and risk prioritization on mortality in the US
title_full The impacts of COVID-19 vaccine timing, number of doses, and risk prioritization on mortality in the US
title_fullStr The impacts of COVID-19 vaccine timing, number of doses, and risk prioritization on mortality in the US
title_full_unstemmed The impacts of COVID-19 vaccine timing, number of doses, and risk prioritization on mortality in the US
title_short The impacts of COVID-19 vaccine timing, number of doses, and risk prioritization on mortality in the US
title_sort impacts of covid-19 vaccine timing, number of doses, and risk prioritization on mortality in the us
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7836125/
https://www.ncbi.nlm.nih.gov/pubmed/33501453
http://dx.doi.org/10.1101/2021.01.18.21250071
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