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LINC00680 enhances hepatocellular carcinoma stemness behavior and chemoresistance by sponging miR-568 to upregulate AKT3

BACKGROUND: Hepatocellular carcinoma (HCC) has an extremely poor prognosis due to the development of chemoresistance, coupled with inherently increased stemness properties. Long non-coding RNAs (LncRNAs) are key regulators for tumor cell stemness and chemosensitivity. Currently the relevance between...

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Detalles Bibliográficos
Autores principales: Shu, Gege, Su, Huizhao, Wang, Zhiqian, Lai, Shihui, Wang, Yan, Liu, Xiaomeng, Dai, Luo, Bi, Yin, Chen, Wei, Huang, Weiyu, Zhou, Ziyan, He, Songqing, Dai, Hongliang, Tang, Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7836199/
https://www.ncbi.nlm.nih.gov/pubmed/33499874
http://dx.doi.org/10.1186/s13046-021-01854-5