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Detection of human auditory evoked brain signals with a resilient nonlinear optically pumped magnetometer

Optically Pumped Magnetometers (OPMs) have been hailed as the future of human magnetoencephalography, as they enable a level of flexibility and adaptability that cannot be obtained with systems based on superconductors. While OPM sensors are already commercially available, there is plenty of room fo...

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Autores principales: Kowalczyk, Anna U., Bezsudnova, Yulia, Jensen, Ole, Barontini, Giovanni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Academic Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7836231/
https://www.ncbi.nlm.nih.gov/pubmed/33132074
http://dx.doi.org/10.1016/j.neuroimage.2020.117497
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author Kowalczyk, Anna U.
Bezsudnova, Yulia
Jensen, Ole
Barontini, Giovanni
author_facet Kowalczyk, Anna U.
Bezsudnova, Yulia
Jensen, Ole
Barontini, Giovanni
author_sort Kowalczyk, Anna U.
collection PubMed
description Optically Pumped Magnetometers (OPMs) have been hailed as the future of human magnetoencephalography, as they enable a level of flexibility and adaptability that cannot be obtained with systems based on superconductors. While OPM sensors are already commercially available, there is plenty of room for further improvements and customization. In this work, we detected auditory evoked brain fields using an OPM based on the nonlinear magneto-optical rotation (NMOR) technique. Our sensor head, containing only optical and non-magnetizable elements, is connected to an external module including all the electronic components, placed outside the magnetically shielded room. The use of the NMOR allowed us to detect the brain signals in non-zero magnetic field environments. In particular, we were able to detect auditory evoked fields in a background field of 70 nT. We benchmarked our sensor with conventional SQUID sensors, showing comparable performance. We further demonstrated that our sensor can be employed to detect modulations of brain oscillations in the alpha band. Our results are a promising stepping-stone towards the realization of resilient OPM-based magnetoencephalography systems that do not require active compensation.
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spelling pubmed-78362312021-02-01 Detection of human auditory evoked brain signals with a resilient nonlinear optically pumped magnetometer Kowalczyk, Anna U. Bezsudnova, Yulia Jensen, Ole Barontini, Giovanni Neuroimage Article Optically Pumped Magnetometers (OPMs) have been hailed as the future of human magnetoencephalography, as they enable a level of flexibility and adaptability that cannot be obtained with systems based on superconductors. While OPM sensors are already commercially available, there is plenty of room for further improvements and customization. In this work, we detected auditory evoked brain fields using an OPM based on the nonlinear magneto-optical rotation (NMOR) technique. Our sensor head, containing only optical and non-magnetizable elements, is connected to an external module including all the electronic components, placed outside the magnetically shielded room. The use of the NMOR allowed us to detect the brain signals in non-zero magnetic field environments. In particular, we were able to detect auditory evoked fields in a background field of 70 nT. We benchmarked our sensor with conventional SQUID sensors, showing comparable performance. We further demonstrated that our sensor can be employed to detect modulations of brain oscillations in the alpha band. Our results are a promising stepping-stone towards the realization of resilient OPM-based magnetoencephalography systems that do not require active compensation. Academic Press 2021-02-01 /pmc/articles/PMC7836231/ /pubmed/33132074 http://dx.doi.org/10.1016/j.neuroimage.2020.117497 Text en Crown Copyright © 2020 Published by Elsevier Inc. http://creativecommons.org/licenses/by/4.0/ This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Kowalczyk, Anna U.
Bezsudnova, Yulia
Jensen, Ole
Barontini, Giovanni
Detection of human auditory evoked brain signals with a resilient nonlinear optically pumped magnetometer
title Detection of human auditory evoked brain signals with a resilient nonlinear optically pumped magnetometer
title_full Detection of human auditory evoked brain signals with a resilient nonlinear optically pumped magnetometer
title_fullStr Detection of human auditory evoked brain signals with a resilient nonlinear optically pumped magnetometer
title_full_unstemmed Detection of human auditory evoked brain signals with a resilient nonlinear optically pumped magnetometer
title_short Detection of human auditory evoked brain signals with a resilient nonlinear optically pumped magnetometer
title_sort detection of human auditory evoked brain signals with a resilient nonlinear optically pumped magnetometer
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7836231/
https://www.ncbi.nlm.nih.gov/pubmed/33132074
http://dx.doi.org/10.1016/j.neuroimage.2020.117497
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