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Advancements in stem cell-derived hepatocyte-like cell models for hepatotoxicity testing

Drug-induced liver injury (DILI) is one of the leading causes of clinical trial failures and high drug attrition rates. Currently, the commonly used hepatocyte models include primary human hepatocytes (PHHs), animal models, and hepatic cell lines. However, these models have disadvantages that includ...

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Detalles Bibliográficos
Autores principales:	Jin, Meixian, Yi, Xiao, Liao, Wei, Chen, Qi, Yang, Wanren, Li, Yang, Li, Shao, Gao, Yi, Peng, Qing, Zhou, Shuqin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7836452/ https://www.ncbi.nlm.nih.gov/pubmed/33494782 http://dx.doi.org/10.1186/s13287-021-02152-9

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