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Regulator of cullins-1 (ROC1) negatively regulates the Gli2 regulator SUFU to activate the hedgehog pathway in bladder cancer

BACKGROUND: The regulator of cullins-1 (ROC1) is an essential subunit in the cullin-RING ligase (CRL) protein complex and has been shown to be critical in bladder cancer cell survival and progression. This study aimed to explore the molecular mechanism of ROC1 action in the malignant progression of...

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Detalles Bibliográficos
Autores principales:	Wang, W., Qiu, J., Qu, P., Chen, H., Lan, J., Li, L., Gu, M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Primary Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7836478/ https://www.ncbi.nlm.nih.gov/pubmed/33499884 http://dx.doi.org/10.1186/s12935-021-01775-5

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