Higher interleukin-6 levels and changes in transforming growth factor-β are associated with lung impairment in pulmonary tuberculosis

Higher levels of IL-6 and slow-to-resolve TGF-β are associated with lung impairment in treated tuberculosis. These results have important implications for clinical trials of immunomodulatory therapies to prevent tuberculosis-associated lung disease. https://bit.ly/2FQEtsz

Detalles Bibliográficos
Autores principales: Gupte, Akshay N., Selvaraju, Sriram, Gaikwad, Sanjay, Mave, Vidya, Kumar, Pavan, Babu, Subash, Andrade, Bruno B., Checkley, William, Bollinger, Robert, Gupta, Amita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Respiratory Society 2021
Materias:
Original Research Letters
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7836581/
https://www.ncbi.nlm.nih.gov/pubmed/33532468
http://dx.doi.org/10.1183/23120541.00390-2020
Descripción
Sumario:Higher levels of IL-6 and slow-to-resolve TGF-β are associated with lung impairment in treated tuberculosis. These results have important implications for clinical trials of immunomodulatory therapies to prevent tuberculosis-associated lung disease. https://bit.ly/2FQEtsz

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