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Higher interleukin-6 levels and changes in transforming growth factor-β are associated with lung impairment in pulmonary tuberculosis

Higher levels of IL-6 and slow-to-resolve TGF-β are associated with lung impairment in treated tuberculosis. These results have important implications for clinical trials of immunomodulatory therapies to prevent tuberculosis-associated lung disease. https://bit.ly/2FQEtsz

Detalles Bibliográficos
Autores principales: Gupte, Akshay N., Selvaraju, Sriram, Gaikwad, Sanjay, Mave, Vidya, Kumar, Pavan, Babu, Subash, Andrade, Bruno B., Checkley, William, Bollinger, Robert, Gupta, Amita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Respiratory Society 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7836581/
https://www.ncbi.nlm.nih.gov/pubmed/33532468
http://dx.doi.org/10.1183/23120541.00390-2020
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author Gupte, Akshay N.
Selvaraju, Sriram
Gaikwad, Sanjay
Mave, Vidya
Kumar, Pavan
Babu, Subash
Andrade, Bruno B.
Checkley, William
Bollinger, Robert
Gupta, Amita
author_facet Gupte, Akshay N.
Selvaraju, Sriram
Gaikwad, Sanjay
Mave, Vidya
Kumar, Pavan
Babu, Subash
Andrade, Bruno B.
Checkley, William
Bollinger, Robert
Gupta, Amita
author_sort Gupte, Akshay N.
collection PubMed
description Higher levels of IL-6 and slow-to-resolve TGF-β are associated with lung impairment in treated tuberculosis. These results have important implications for clinical trials of immunomodulatory therapies to prevent tuberculosis-associated lung disease. https://bit.ly/2FQEtsz
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spelling pubmed-78365812021-02-01 Higher interleukin-6 levels and changes in transforming growth factor-β are associated with lung impairment in pulmonary tuberculosis Gupte, Akshay N. Selvaraju, Sriram Gaikwad, Sanjay Mave, Vidya Kumar, Pavan Babu, Subash Andrade, Bruno B. Checkley, William Bollinger, Robert Gupta, Amita ERJ Open Res Original Research Letters Higher levels of IL-6 and slow-to-resolve TGF-β are associated with lung impairment in treated tuberculosis. These results have important implications for clinical trials of immunomodulatory therapies to prevent tuberculosis-associated lung disease. https://bit.ly/2FQEtsz European Respiratory Society 2021-01-18 /pmc/articles/PMC7836581/ /pubmed/33532468 http://dx.doi.org/10.1183/23120541.00390-2020 Text en Copyright ©ERS 2021 http://creativecommons.org/licenses/by-nc/4.0/This article is open access and distributed under the terms of the Creative Commons Attribution Non-Commercial Licence 4.0.
spellingShingle Original Research Letters
Gupte, Akshay N.
Selvaraju, Sriram
Gaikwad, Sanjay
Mave, Vidya
Kumar, Pavan
Babu, Subash
Andrade, Bruno B.
Checkley, William
Bollinger, Robert
Gupta, Amita
Higher interleukin-6 levels and changes in transforming growth factor-β are associated with lung impairment in pulmonary tuberculosis
title Higher interleukin-6 levels and changes in transforming growth factor-β are associated with lung impairment in pulmonary tuberculosis
title_full Higher interleukin-6 levels and changes in transforming growth factor-β are associated with lung impairment in pulmonary tuberculosis
title_fullStr Higher interleukin-6 levels and changes in transforming growth factor-β are associated with lung impairment in pulmonary tuberculosis
title_full_unstemmed Higher interleukin-6 levels and changes in transforming growth factor-β are associated with lung impairment in pulmonary tuberculosis
title_short Higher interleukin-6 levels and changes in transforming growth factor-β are associated with lung impairment in pulmonary tuberculosis
title_sort higher interleukin-6 levels and changes in transforming growth factor-β are associated with lung impairment in pulmonary tuberculosis
topic Original Research Letters
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7836581/
https://www.ncbi.nlm.nih.gov/pubmed/33532468
http://dx.doi.org/10.1183/23120541.00390-2020
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