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Higher interleukin-6 levels and changes in transforming growth factor-β are associated with lung impairment in pulmonary tuberculosis
Higher levels of IL-6 and slow-to-resolve TGF-β are associated with lung impairment in treated tuberculosis. These results have important implications for clinical trials of immunomodulatory therapies to prevent tuberculosis-associated lung disease. https://bit.ly/2FQEtsz
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
European Respiratory Society
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7836581/ https://www.ncbi.nlm.nih.gov/pubmed/33532468 http://dx.doi.org/10.1183/23120541.00390-2020 |
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author | Gupte, Akshay N. Selvaraju, Sriram Gaikwad, Sanjay Mave, Vidya Kumar, Pavan Babu, Subash Andrade, Bruno B. Checkley, William Bollinger, Robert Gupta, Amita |
author_facet | Gupte, Akshay N. Selvaraju, Sriram Gaikwad, Sanjay Mave, Vidya Kumar, Pavan Babu, Subash Andrade, Bruno B. Checkley, William Bollinger, Robert Gupta, Amita |
author_sort | Gupte, Akshay N. |
collection | PubMed |
description | Higher levels of IL-6 and slow-to-resolve TGF-β are associated with lung impairment in treated tuberculosis. These results have important implications for clinical trials of immunomodulatory therapies to prevent tuberculosis-associated lung disease. https://bit.ly/2FQEtsz |
format | Online Article Text |
id | pubmed-7836581 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | European Respiratory Society |
record_format | MEDLINE/PubMed |
spelling | pubmed-78365812021-02-01 Higher interleukin-6 levels and changes in transforming growth factor-β are associated with lung impairment in pulmonary tuberculosis Gupte, Akshay N. Selvaraju, Sriram Gaikwad, Sanjay Mave, Vidya Kumar, Pavan Babu, Subash Andrade, Bruno B. Checkley, William Bollinger, Robert Gupta, Amita ERJ Open Res Original Research Letters Higher levels of IL-6 and slow-to-resolve TGF-β are associated with lung impairment in treated tuberculosis. These results have important implications for clinical trials of immunomodulatory therapies to prevent tuberculosis-associated lung disease. https://bit.ly/2FQEtsz European Respiratory Society 2021-01-18 /pmc/articles/PMC7836581/ /pubmed/33532468 http://dx.doi.org/10.1183/23120541.00390-2020 Text en Copyright ©ERS 2021 http://creativecommons.org/licenses/by-nc/4.0/This article is open access and distributed under the terms of the Creative Commons Attribution Non-Commercial Licence 4.0. |
spellingShingle | Original Research Letters Gupte, Akshay N. Selvaraju, Sriram Gaikwad, Sanjay Mave, Vidya Kumar, Pavan Babu, Subash Andrade, Bruno B. Checkley, William Bollinger, Robert Gupta, Amita Higher interleukin-6 levels and changes in transforming growth factor-β are associated with lung impairment in pulmonary tuberculosis |
title | Higher interleukin-6 levels and changes in transforming growth factor-β are associated with lung impairment in pulmonary tuberculosis |
title_full | Higher interleukin-6 levels and changes in transforming growth factor-β are associated with lung impairment in pulmonary tuberculosis |
title_fullStr | Higher interleukin-6 levels and changes in transforming growth factor-β are associated with lung impairment in pulmonary tuberculosis |
title_full_unstemmed | Higher interleukin-6 levels and changes in transforming growth factor-β are associated with lung impairment in pulmonary tuberculosis |
title_short | Higher interleukin-6 levels and changes in transforming growth factor-β are associated with lung impairment in pulmonary tuberculosis |
title_sort | higher interleukin-6 levels and changes in transforming growth factor-β are associated with lung impairment in pulmonary tuberculosis |
topic | Original Research Letters |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7836581/ https://www.ncbi.nlm.nih.gov/pubmed/33532468 http://dx.doi.org/10.1183/23120541.00390-2020 |
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