Hypoxia promotes the metastasis of pancreatic cancer through regulating NOX4/KDM5A-mediated histone methylation modification changes in a HIF1A-independent manner

BACKGROUND: Hypoxia is a characteristic of the tumor microenvironments within pancreatic cancer (PC), which has been linked to its malignancy. Recently, hypoxia has been reported to regulate the activity of important carcinogenic pathways by changing the status of histone modification. NOX4, a membe...

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Detalles Bibliográficos
Autores principales: Li, Hongzhen, Peng, Chunyan, Zhu, Chenhui, Nie, Shuang, Qian, Xuetian, Shi, Zhao, Shi, Mengyue, Liang, Yan, Ding, Xiwei, Zhang, Shu, Zhang, Bin, Li, Xihan, Xu, Guifang, Lv, Ying, Wang, Lei, Friess, Helmut, Kong, Bo, Zou, Xiaoping, Shen, Shanshan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7836598/
https://www.ncbi.nlm.nih.gov/pubmed/33499904
http://dx.doi.org/10.1186/s13148-021-01016-6

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