Extended lifespan of bronchial epithelial cells maintains normal cellular phenotype and transcriptome integrity

Genetic studies have identified several epithelial-derived genes associated with airway diseases. However, techniques used to study gene function frequently exceed the proliferative potential of primary human bronchial epithelial cells (HBECs) isolated from patients. Increased expression of the poly...

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Detalles Bibliográficos
Autores principales: O'Loughlin, Jonathan, Hall, Robert J., Bhaker, Sangita, Portelli, Michael A., Henry, Amanda, Pang, Vincent, Bates, David O., Sharp, Tyson V., Sayers, Ian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Respiratory Society 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7836642/
https://www.ncbi.nlm.nih.gov/pubmed/33532474
http://dx.doi.org/10.1183/23120541.00254-2020

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