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Dendritic cell vaccine immunotherapy; the beginning of the end of cancer and COVID-19. A hypothesis

Immunotherapy is the newest approach to combat cancer. It can be achieved using several strategies, among which is the dendritic cell (DC) vaccine therapy. Several clinical trials are ongoing using DC vaccine therapy either as a sole agent or in combination with other interventions to tackle differe...

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Detalles Bibliográficos
Autores principales: Saadeldin, Mona Kamal, Abdel-Aziz, Amal Kamal, Abdellatif, Ahmed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7836805/
https://www.ncbi.nlm.nih.gov/pubmed/33221134
http://dx.doi.org/10.1016/j.mehy.2020.110365
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author Saadeldin, Mona Kamal
Abdel-Aziz, Amal Kamal
Abdellatif, Ahmed
author_facet Saadeldin, Mona Kamal
Abdel-Aziz, Amal Kamal
Abdellatif, Ahmed
author_sort Saadeldin, Mona Kamal
collection PubMed
description Immunotherapy is the newest approach to combat cancer. It can be achieved using several strategies, among which is the dendritic cell (DC) vaccine therapy. Several clinical trials are ongoing using DC vaccine therapy either as a sole agent or in combination with other interventions to tackle different types of cancer. Immunotherapy can offer a potential treatment to coronavirus disease 2019 (COVID-19) the worst pandemic facing this generation, a disease with deleterious effects on the health and economic systems worldwide. We hypothesize that DC vaccine therapy may provide a potential treatment strategy to help combat COVID-19. Cancer patients are at the top of the vulnerable population owing to their immune-compromised status. In this review, we discuss DC vaccine therapy in the light of the body’s immunity, cancer, and newly emerging infections such as COVID-19 in hopes of better-customized treatment options for patients with multiple comorbidities.
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spelling pubmed-78368052021-01-26 Dendritic cell vaccine immunotherapy; the beginning of the end of cancer and COVID-19. A hypothesis Saadeldin, Mona Kamal Abdel-Aziz, Amal Kamal Abdellatif, Ahmed Med Hypotheses Article Immunotherapy is the newest approach to combat cancer. It can be achieved using several strategies, among which is the dendritic cell (DC) vaccine therapy. Several clinical trials are ongoing using DC vaccine therapy either as a sole agent or in combination with other interventions to tackle different types of cancer. Immunotherapy can offer a potential treatment to coronavirus disease 2019 (COVID-19) the worst pandemic facing this generation, a disease with deleterious effects on the health and economic systems worldwide. We hypothesize that DC vaccine therapy may provide a potential treatment strategy to help combat COVID-19. Cancer patients are at the top of the vulnerable population owing to their immune-compromised status. In this review, we discuss DC vaccine therapy in the light of the body’s immunity, cancer, and newly emerging infections such as COVID-19 in hopes of better-customized treatment options for patients with multiple comorbidities. Elsevier Ltd. 2021-01 2020-11-09 /pmc/articles/PMC7836805/ /pubmed/33221134 http://dx.doi.org/10.1016/j.mehy.2020.110365 Text en © 2020 Elsevier Ltd. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Saadeldin, Mona Kamal
Abdel-Aziz, Amal Kamal
Abdellatif, Ahmed
Dendritic cell vaccine immunotherapy; the beginning of the end of cancer and COVID-19. A hypothesis
title Dendritic cell vaccine immunotherapy; the beginning of the end of cancer and COVID-19. A hypothesis
title_full Dendritic cell vaccine immunotherapy; the beginning of the end of cancer and COVID-19. A hypothesis
title_fullStr Dendritic cell vaccine immunotherapy; the beginning of the end of cancer and COVID-19. A hypothesis
title_full_unstemmed Dendritic cell vaccine immunotherapy; the beginning of the end of cancer and COVID-19. A hypothesis
title_short Dendritic cell vaccine immunotherapy; the beginning of the end of cancer and COVID-19. A hypothesis
title_sort dendritic cell vaccine immunotherapy; the beginning of the end of cancer and covid-19. a hypothesis
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7836805/
https://www.ncbi.nlm.nih.gov/pubmed/33221134
http://dx.doi.org/10.1016/j.mehy.2020.110365
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