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The Molecular Mechanism of Domain Swapping of the C-Terminal Domain of the SARS-Coronavirus Main Protease

In three-dimensional domain swapping, two protein monomers exchange a part of their structures to form an intertwined homodimer, whose subunits resemble the monomer. Several viral proteins domain swap to increase their structural complexity or functional avidity. The main protease (M(pro)) of the se...

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Detalles Bibliográficos
Autores principales: Terse, Vishram L., Gosavi, Shachi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Biophysical Society 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7837137/
https://www.ncbi.nlm.nih.gov/pubmed/33359834
http://dx.doi.org/10.1016/j.bpj.2020.11.2277