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A novel LysR‐type regulator negatively affects biosynthesis of the immunosuppressant brasilicardin

Brasilicardin A (BraA) is a promising immunosuppressive compound produced naturally by the pathogenic bacterium Nocardia terpenica IFM 0406. Heterologous host expression of brasilicardin gene cluster showed to be efficient to bypass the safety issues, low production levels and lack of genetic tools...

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Detalles Bibliográficos
Autores principales:	Wolański, Marcin, Krawiec, Michał, Schwarz, Paul N., Stegmann, Evi, Wohlleben, Wolfgang, Buchmann, Anina, Gross, Harald, Eitel, Michael, Koch, Pierre, Botas, Alma, Méndez, Carmen, Núñez, Luz Elena, Morís, Francisco, Cortés, Jesus, Zakrzewska‐Czerwińska, Jolanta
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2020
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7837296/ https://www.ncbi.nlm.nih.gov/pubmed/33531886 http://dx.doi.org/10.1002/elsc.202000038

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