Angiotensin II Type 1 Receptor Autoantibodies in Primary Aldosteronism

Primary aldosteronism (PA) is the most common form of endocrine hypertension. Agonistic autoantibodies against the angiotensin II type 1 receptor (AT (1) R-Abs) have been described in transplantation medicine and women with pre-eclampsia and more recently in patients with PA. Any functional role of...

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Detalles Bibliográficos
Autores principales: Meyer, Lucie S., Gong, Siyuan, Reincke, Martin, Williams, Tracy Ann
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Georg Thieme Verlag KG 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7837338/
https://www.ncbi.nlm.nih.gov/pubmed/32168525
http://dx.doi.org/10.1055/a-1120-8647
Descripción
Sumario:Primary aldosteronism (PA) is the most common form of endocrine hypertension. Agonistic autoantibodies against the angiotensin II type 1 receptor (AT (1) R-Abs) have been described in transplantation medicine and women with pre-eclampsia and more recently in patients with PA. Any functional role of AT (1) R-Abs in either of the two main subtypes of PA (aldosterone-producing adenoma or bilateral adrenal hyperplasia) requires clarification. In this review, we discuss the studies performed to date on AT (1) R-Abs in PA.

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