Angiotensin II Type 1 Receptor Autoantibodies in Primary Aldosteronism

Primary aldosteronism (PA) is the most common form of endocrine hypertension. Agonistic autoantibodies against the angiotensin II type 1 receptor (AT (1) R-Abs) have been described in transplantation medicine and women with pre-eclampsia and more recently in patients with PA. Any functional role of...

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Autores principales: Meyer, Lucie S., Gong, Siyuan, Reincke, Martin, Williams, Tracy Ann
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Georg Thieme Verlag KG 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7837338/
https://www.ncbi.nlm.nih.gov/pubmed/32168525
http://dx.doi.org/10.1055/a-1120-8647
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author Meyer, Lucie S.
Gong, Siyuan
Reincke, Martin
Williams, Tracy Ann
author_facet Meyer, Lucie S.
Gong, Siyuan
Reincke, Martin
Williams, Tracy Ann
author_sort Meyer, Lucie S.
collection PubMed
description Primary aldosteronism (PA) is the most common form of endocrine hypertension. Agonistic autoantibodies against the angiotensin II type 1 receptor (AT (1) R-Abs) have been described in transplantation medicine and women with pre-eclampsia and more recently in patients with PA. Any functional role of AT (1) R-Abs in either of the two main subtypes of PA (aldosterone-producing adenoma or bilateral adrenal hyperplasia) requires clarification. In this review, we discuss the studies performed to date on AT (1) R-Abs in PA.
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spelling pubmed-78373382021-01-28 Angiotensin II Type 1 Receptor Autoantibodies in Primary Aldosteronism Meyer, Lucie S. Gong, Siyuan Reincke, Martin Williams, Tracy Ann Horm Metab Res Primary aldosteronism (PA) is the most common form of endocrine hypertension. Agonistic autoantibodies against the angiotensin II type 1 receptor (AT (1) R-Abs) have been described in transplantation medicine and women with pre-eclampsia and more recently in patients with PA. Any functional role of AT (1) R-Abs in either of the two main subtypes of PA (aldosterone-producing adenoma or bilateral adrenal hyperplasia) requires clarification. In this review, we discuss the studies performed to date on AT (1) R-Abs in PA. Georg Thieme Verlag KG 2020-03-13 2020-06 /pmc/articles/PMC7837338/ /pubmed/32168525 http://dx.doi.org/10.1055/a-1120-8647 Text en The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/). https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License, which permits unrestricted reproduction and distribution, for non-commercial purposes only; and use and reproduction, but not distribution, of adapted material for non-commercial purposes only, provided the original work is properly cited.
spellingShingle Meyer, Lucie S.
Gong, Siyuan
Reincke, Martin
Williams, Tracy Ann
Angiotensin II Type 1 Receptor Autoantibodies in Primary Aldosteronism
title Angiotensin II Type 1 Receptor Autoantibodies in Primary Aldosteronism
title_full Angiotensin II Type 1 Receptor Autoantibodies in Primary Aldosteronism
title_fullStr Angiotensin II Type 1 Receptor Autoantibodies in Primary Aldosteronism
title_full_unstemmed Angiotensin II Type 1 Receptor Autoantibodies in Primary Aldosteronism
title_short Angiotensin II Type 1 Receptor Autoantibodies in Primary Aldosteronism
title_sort angiotensin ii type 1 receptor autoantibodies in primary aldosteronism
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7837338/
https://www.ncbi.nlm.nih.gov/pubmed/32168525
http://dx.doi.org/10.1055/a-1120-8647
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AT reinckemartin angiotensiniitype1receptorautoantibodiesinprimaryaldosteronism
AT williamstracyann angiotensiniitype1receptorautoantibodiesinprimaryaldosteronism

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