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Glycolytic expression in lower-grade glioma reveals an epigenetic association between IDH mutation status and PDL1/2 expression

BACKGROUND: The interplay between glycolysis and immunosuppression in cancer has recently emerged as an intriguing area of research. The aim of this study was to elucidate a potential epigenetic link between glycolysis, isocitrate hydrogenase (IDH) status, and immune checkpoint expression in human l...

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Detalles Bibliográficos
Autores principales: Givechian, Kevin B, Garner, Chad, Benz, Steve, Rabizadeh, Shahrooz, Soon-Shiong, Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7837356/
https://www.ncbi.nlm.nih.gov/pubmed/33532725
http://dx.doi.org/10.1093/noajnl/vdaa162