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Tackle the free radicals damage in COVID-19
COVID-19 is a severe pandemic which has caused a devastating amount of loss in lives around the world, and yet we still don't know how to appropriately treat this disease. We know very little about the pathogenesis of SARS-CoV-2, the virus which induces the COVID-19. However, COVID-19 does shar...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7837363/ https://www.ncbi.nlm.nih.gov/pubmed/32562746 http://dx.doi.org/10.1016/j.niox.2020.06.002 |
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author | Wu, Jun |
author_facet | Wu, Jun |
author_sort | Wu, Jun |
collection | PubMed |
description | COVID-19 is a severe pandemic which has caused a devastating amount of loss in lives around the world, and yet we still don't know how to appropriately treat this disease. We know very little about the pathogenesis of SARS-CoV-2, the virus which induces the COVID-19. However, COVID-19 does share many similar symptoms with SARS and influenza. Previous scientific discoveries learned from lab animal models and clinical practices shed light on possible pathogenic mechanisms in COVID-19. In the past decades, accumulated scientific findings confirmed the pathogenic role of free radicals damage in respiratory virus infection. Astonishingly very few medical professionals mention the crucial role of free radical damage in COVID-19. This hypothesis aims to summarize the crucial pathogenic role of free radical damage in respiratory virus induced pneumonia and suggest an antioxidative therapeutic strategy for COVID-19. |
format | Online Article Text |
id | pubmed-7837363 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Elsevier Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-78373632021-01-27 Tackle the free radicals damage in COVID-19 Wu, Jun Nitric Oxide Review COVID-19 is a severe pandemic which has caused a devastating amount of loss in lives around the world, and yet we still don't know how to appropriately treat this disease. We know very little about the pathogenesis of SARS-CoV-2, the virus which induces the COVID-19. However, COVID-19 does share many similar symptoms with SARS and influenza. Previous scientific discoveries learned from lab animal models and clinical practices shed light on possible pathogenic mechanisms in COVID-19. In the past decades, accumulated scientific findings confirmed the pathogenic role of free radicals damage in respiratory virus infection. Astonishingly very few medical professionals mention the crucial role of free radical damage in COVID-19. This hypothesis aims to summarize the crucial pathogenic role of free radical damage in respiratory virus induced pneumonia and suggest an antioxidative therapeutic strategy for COVID-19. Elsevier Inc. 2020-09-01 2020-06-17 /pmc/articles/PMC7837363/ /pubmed/32562746 http://dx.doi.org/10.1016/j.niox.2020.06.002 Text en © 2020 Elsevier Inc. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active. |
spellingShingle | Review Wu, Jun Tackle the free radicals damage in COVID-19 |
title | Tackle the free radicals damage in COVID-19 |
title_full | Tackle the free radicals damage in COVID-19 |
title_fullStr | Tackle the free radicals damage in COVID-19 |
title_full_unstemmed | Tackle the free radicals damage in COVID-19 |
title_short | Tackle the free radicals damage in COVID-19 |
title_sort | tackle the free radicals damage in covid-19 |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7837363/ https://www.ncbi.nlm.nih.gov/pubmed/32562746 http://dx.doi.org/10.1016/j.niox.2020.06.002 |
work_keys_str_mv | AT wujun tacklethefreeradicalsdamageincovid19 |