Influenza, but not SARS‐CoV‐2, infection induces a rapid interferon response that wanes with age and diminished tissue‐resident memory CD8(+) T cells

Older individuals exhibit a diminished ability to respond to and clear respiratory pathogens and, as such, experience a higher rate of lung infections with a higher mortality rate. It is unclear why respiratory pathogens impact older people disproportionately. Using human lung tissue from donors age...

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Detalles Bibliográficos
Autores principales: Nguyen, Thi HO, McAuley, Julie L, Kim, Youry, Zheng, Ming ZM, Gherardin, Nicholas A, Godfrey, Dale I, Purcell, Damian FJ, Sullivan, Lucy C, Westall, Glen P, Reading, Patrick C, Kedzierska, Katherine, Wakim, Linda M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7837404/
https://www.ncbi.nlm.nih.gov/pubmed/33532071
http://dx.doi.org/10.1002/cti2.1242

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