A live attenuated-vaccine model confers cross-protective immunity against different species of the Leptospira genus

Leptospirosis is the leading zoonotic disease in terms of morbidity and mortality worldwide. Effective prevention is urgently needed as the drivers of disease transmission continue to intensify. The key challenge has been developing a widely applicable vaccine that protects against the >300 serov...

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Detalles Bibliográficos
Autores principales: Wunder, Elsio A, Adhikarla, Haritha, Hamond, Camila, Owers Bonner, Katharine A, Liang, Li, Rodrigues, Camila B, Bisht, Vimla, Nally, Jarlath E, Alt, David P, Reis, Mitermayer G, Diggle, Peter J, Felgner, Philip L, Ko, Albert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Microbiology and Infectious Disease
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7837694/
https://www.ncbi.nlm.nih.gov/pubmed/33496263
http://dx.doi.org/10.7554/eLife.64166

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7837694/
https://www.ncbi.nlm.nih.gov/pubmed/33496263
http://dx.doi.org/10.7554/eLife.64166

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