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A live attenuated-vaccine model confers cross-protective immunity against different species of the Leptospira genus
Leptospirosis is the leading zoonotic disease in terms of morbidity and mortality worldwide. Effective prevention is urgently needed as the drivers of disease transmission continue to intensify. The key challenge has been developing a widely applicable vaccine that protects against the >300 serov...
Autores principales: | Wunder, Elsio A, Adhikarla, Haritha, Hamond, Camila, Owers Bonner, Katharine A, Liang, Li, Rodrigues, Camila B, Bisht, Vimla, Nally, Jarlath E, Alt, David P, Reis, Mitermayer G, Diggle, Peter J, Felgner, Philip L, Ko, Albert |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7837694/ https://www.ncbi.nlm.nih.gov/pubmed/33496263 http://dx.doi.org/10.7554/eLife.64166 |
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