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Renal Function Improvement Following ANG-3777 Treatment in Patients at High Risk for Delayed Graft Function After Kidney Transplantation

BACKGROUND. Patients (20%–50%) undergoing renal transplantation experience acute kidney injury resulting in delayed graft function. ANG-3777 is an hepatocyte growth factor mimetic that binds to the c-MET receptor. In animal models, ANG-3777 decreases apoptosis, increases proliferation, and promotes...

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Detalles Bibliográficos
Autores principales: Bromberg, Jonathan S., Weir, Matthew R., Gaber, A. Osama, Yamin, Michael A., Goldberg, Itzhak D., Mayne, Tracy J., Cal, Weizhong, Cooper, Matthew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7837751/
https://www.ncbi.nlm.nih.gov/pubmed/32265417
http://dx.doi.org/10.1097/TP.0000000000003255