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Efficacy of minimally invasive surgery for the treatment of hypertensive intracerebral hemorrhage: A protocol of randomized controlled trial
INTRODUCTION: Hypertensive intracerebral hemorrhage (HICH) is the most serious complication of hypertension. Clearing intracranial hematoma as soon as possible, reducing brain cell edema, and controlling intracranial pressure could effectively reduce neuron damage, lower patient mortality, and impro...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott Williams & Wilkins
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7837866/ https://www.ncbi.nlm.nih.gov/pubmed/33546039 http://dx.doi.org/10.1097/MD.0000000000024213 |
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author | Liu, Jiang Cheng, Jing Zhou, Hongjun Deng, Chunyan Wang, Zhengxin |
author_facet | Liu, Jiang Cheng, Jing Zhou, Hongjun Deng, Chunyan Wang, Zhengxin |
author_sort | Liu, Jiang |
collection | PubMed |
description | INTRODUCTION: Hypertensive intracerebral hemorrhage (HICH) is the most serious complication of hypertension. Clearing intracranial hematoma as soon as possible, reducing brain cell edema, and controlling intracranial pressure could effectively reduce neuron damage, lower patient mortality, and improve patient prognosis. At present, minimally invasive surgery (MIS) has been widely used and plays an important role in the treatment of HICH. However, it is still in controversies about the choice of surgical treatment and medication treatment for HICH. Therefore, we try to conduct a randomized, controlled, prospective trial to observe the efficacy of MIS treatment against HICH compared with medication treatment. METHODS: Patients will be randomly divided into treatment group and control group in a 1:1 ratio using the random number generator in Microsoft Excel. Stereotactic soft channel minimally invasive intracranial hematoma puncture and drainage treatment and medication treatment will be applied respectively. The outcomes of intracerebral hemorrhage volume, Glasgow coma scale, National Institutes of Health Stroke Scale will be recorded. CONCLUSIONS: The findings of the study will be helpful for the choice of MIS and conservative treatment when treating HICH patients. TRIAL REGISTRATION: OSF Registration number: DOI 10.17605/OSF.IO/ME6Y5. |
format | Online Article Text |
id | pubmed-7837866 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Lippincott Williams & Wilkins |
record_format | MEDLINE/PubMed |
spelling | pubmed-78378662021-01-27 Efficacy of minimally invasive surgery for the treatment of hypertensive intracerebral hemorrhage: A protocol of randomized controlled trial Liu, Jiang Cheng, Jing Zhou, Hongjun Deng, Chunyan Wang, Zhengxin Medicine (Baltimore) 5300 INTRODUCTION: Hypertensive intracerebral hemorrhage (HICH) is the most serious complication of hypertension. Clearing intracranial hematoma as soon as possible, reducing brain cell edema, and controlling intracranial pressure could effectively reduce neuron damage, lower patient mortality, and improve patient prognosis. At present, minimally invasive surgery (MIS) has been widely used and plays an important role in the treatment of HICH. However, it is still in controversies about the choice of surgical treatment and medication treatment for HICH. Therefore, we try to conduct a randomized, controlled, prospective trial to observe the efficacy of MIS treatment against HICH compared with medication treatment. METHODS: Patients will be randomly divided into treatment group and control group in a 1:1 ratio using the random number generator in Microsoft Excel. Stereotactic soft channel minimally invasive intracranial hematoma puncture and drainage treatment and medication treatment will be applied respectively. The outcomes of intracerebral hemorrhage volume, Glasgow coma scale, National Institutes of Health Stroke Scale will be recorded. CONCLUSIONS: The findings of the study will be helpful for the choice of MIS and conservative treatment when treating HICH patients. TRIAL REGISTRATION: OSF Registration number: DOI 10.17605/OSF.IO/ME6Y5. Lippincott Williams & Wilkins 2021-01-22 /pmc/articles/PMC7837866/ /pubmed/33546039 http://dx.doi.org/10.1097/MD.0000000000024213 Text en Copyright © 2021 the Author(s). Published by Wolters Kluwer Health, Inc. http://creativecommons.org/licenses/by/4.0 This is an open access article distributed under the Creative Commons Attribution License 4.0 (CCBY), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. http://creativecommons.org/licenses/by/4.0 |
spellingShingle | 5300 Liu, Jiang Cheng, Jing Zhou, Hongjun Deng, Chunyan Wang, Zhengxin Efficacy of minimally invasive surgery for the treatment of hypertensive intracerebral hemorrhage: A protocol of randomized controlled trial |
title | Efficacy of minimally invasive surgery for the treatment of hypertensive intracerebral hemorrhage: A protocol of randomized controlled trial |
title_full | Efficacy of minimally invasive surgery for the treatment of hypertensive intracerebral hemorrhage: A protocol of randomized controlled trial |
title_fullStr | Efficacy of minimally invasive surgery for the treatment of hypertensive intracerebral hemorrhage: A protocol of randomized controlled trial |
title_full_unstemmed | Efficacy of minimally invasive surgery for the treatment of hypertensive intracerebral hemorrhage: A protocol of randomized controlled trial |
title_short | Efficacy of minimally invasive surgery for the treatment of hypertensive intracerebral hemorrhage: A protocol of randomized controlled trial |
title_sort | efficacy of minimally invasive surgery for the treatment of hypertensive intracerebral hemorrhage: a protocol of randomized controlled trial |
topic | 5300 |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7837866/ https://www.ncbi.nlm.nih.gov/pubmed/33546039 http://dx.doi.org/10.1097/MD.0000000000024213 |
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