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Negative pressure wound therapy for skin necrosis prevention after snakebite in the emergency department: A retrospective cohort study

This retrospective cohort study aimed to compare the effectiveness of conventional treatment and ultra-early application of negative pressure wound therapy (NPWT) in patients with snakebites. Patients who visited the emergency department within 24 hours after a snakebite were assigned to the non- NP...

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Detalles Bibliográficos
Autores principales: Kim, Kwan Jae, Min, Jin Hong, Yoo, Insool, Kim, Seung Whan, Lee, Jinwoong, Ryu, Seung, You, Yeon Ho, Park, Jung Soo, Jeong, Won Joon, Cho, Yong Chul, Oh, Se Kwang, In, Yong Nam, Ahn, Hong Joon, Kang, Chang Shin, Kyung, Hyunwoo, Lee, Byung Kook, Lee, Dong Hun, Lee, Dong Hoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7837876/
https://www.ncbi.nlm.nih.gov/pubmed/33546055
http://dx.doi.org/10.1097/MD.0000000000024290
Descripción
Sumario:This retrospective cohort study aimed to compare the effectiveness of conventional treatment and ultra-early application of negative pressure wound therapy (NPWT) in patients with snakebites. Patients who visited the emergency department within 24 hours after a snakebite were assigned to the non- NPWT or NPWT group. Swelling resolution time and rates of necrosis, infection, and operations were compared between the 2 groups. The Stony Brook Scar Evaluation Scale was used to measure short- and long-term wound healing results. Among the included 61 patients, the swelling resolution time was significantly shorter in the NPWT group than in non- NPWT group (P = .010). The NPWT group showed lower necrosis (4.3% versus 36.8%; P = .003) and infection (13.2% and 4.3%; P = .258) rates than the non- NPWT group. The median Stony Brook Scar Evaluation Scale scores were higher in the NPWT group than in the non- NPWT group (P< .001). These findings suggest that ultra-early application of NPWT reduces edema, promotes wound healing, and prevents necrosis in patients with snakebites.