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Dysphagia in Patients With Severe Coronavirus Disease 2019—Potential Neurologic Etiologies

IMPORTANCE: Dysphagia is a common complication of critical illness, and many known risk factors are also present in critically ill coronavirus disease 2019 victims. OBJECTIVES: To investigate dysphagia in patients with severe coronavirus disease 2019. DESIGN, SETTING, AND PARTICIPANTS: In this case...

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Autores principales: Dziewas, Rainer, Hufelschulte, Lisa-Marie, Lepper, Johannes, Sackarnd, Jan, Minnerup, Jens, Teismann, Inga, Ahring, Sigrid, Claus, Inga, Labeit, Bendix, Muhle, Paul, Suntrup-Krüger, Sonja, Warnecke, Tobias, Padberg, Jan-Sören
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7837983/
https://www.ncbi.nlm.nih.gov/pubmed/33521647
http://dx.doi.org/10.1097/CCE.0000000000000332
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author Dziewas, Rainer
Hufelschulte, Lisa-Marie
Lepper, Johannes
Sackarnd, Jan
Minnerup, Jens
Teismann, Inga
Ahring, Sigrid
Claus, Inga
Labeit, Bendix
Muhle, Paul
Suntrup-Krüger, Sonja
Warnecke, Tobias
Padberg, Jan-Sören
author_facet Dziewas, Rainer
Hufelschulte, Lisa-Marie
Lepper, Johannes
Sackarnd, Jan
Minnerup, Jens
Teismann, Inga
Ahring, Sigrid
Claus, Inga
Labeit, Bendix
Muhle, Paul
Suntrup-Krüger, Sonja
Warnecke, Tobias
Padberg, Jan-Sören
author_sort Dziewas, Rainer
collection PubMed
description IMPORTANCE: Dysphagia is a common complication of critical illness, and many known risk factors are also present in critically ill coronavirus disease 2019 victims. OBJECTIVES: To investigate dysphagia in patients with severe coronavirus disease 2019. DESIGN, SETTING, AND PARTICIPANTS: In this case series, we report results of dedicated evaluation of swallowing function in six consecutive, tracheotomized coronavirus disease 2019 patients after they had survived acute respiratory distress syndrome and were weaned from the respirator. MAIN OUTCOMES AND MEASURES: Dysphagia was assessed with flexible endoscopic evaluation of swallowing. RESULTS: Three patients suffered from severe dysphagia and airway compromise precluding decannulation, whereas in the other, three swallowing was less critically impaired, and the tracheal cannula could be removed. Four patients presented with additional laryngeal dysfunctions not typically seen in acute respiratory distress syndrome survivors. CONCLUSION AND RELEVANCE: Dysphagia with impaired airway protection is a key feature in coronavirus disease 2019 acute respiratory distress syndrome survivors. Apart from critical illness polyneuropathy, coronavirus disease 2019–related involvement of the peripheral and central nervous system may contribute to swallowing impairment and laryngeal dysfunction.
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spelling pubmed-78379832021-01-28 Dysphagia in Patients With Severe Coronavirus Disease 2019—Potential Neurologic Etiologies Dziewas, Rainer Hufelschulte, Lisa-Marie Lepper, Johannes Sackarnd, Jan Minnerup, Jens Teismann, Inga Ahring, Sigrid Claus, Inga Labeit, Bendix Muhle, Paul Suntrup-Krüger, Sonja Warnecke, Tobias Padberg, Jan-Sören Crit Care Explor Observational Study IMPORTANCE: Dysphagia is a common complication of critical illness, and many known risk factors are also present in critically ill coronavirus disease 2019 victims. OBJECTIVES: To investigate dysphagia in patients with severe coronavirus disease 2019. DESIGN, SETTING, AND PARTICIPANTS: In this case series, we report results of dedicated evaluation of swallowing function in six consecutive, tracheotomized coronavirus disease 2019 patients after they had survived acute respiratory distress syndrome and were weaned from the respirator. MAIN OUTCOMES AND MEASURES: Dysphagia was assessed with flexible endoscopic evaluation of swallowing. RESULTS: Three patients suffered from severe dysphagia and airway compromise precluding decannulation, whereas in the other, three swallowing was less critically impaired, and the tracheal cannula could be removed. Four patients presented with additional laryngeal dysfunctions not typically seen in acute respiratory distress syndrome survivors. CONCLUSION AND RELEVANCE: Dysphagia with impaired airway protection is a key feature in coronavirus disease 2019 acute respiratory distress syndrome survivors. Apart from critical illness polyneuropathy, coronavirus disease 2019–related involvement of the peripheral and central nervous system may contribute to swallowing impairment and laryngeal dysfunction. Lippincott Williams & Wilkins 2021-01-22 /pmc/articles/PMC7837983/ /pubmed/33521647 http://dx.doi.org/10.1097/CCE.0000000000000332 Text en Copyright © 2021 The Authors. Published by Wolters Kluwer Health, Inc. on behalf of the Society of Critical Care Medicine. This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND) (http://creativecommons.org/licenses/by-nc-nd/4.0/) , where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal.
spellingShingle Observational Study
Dziewas, Rainer
Hufelschulte, Lisa-Marie
Lepper, Johannes
Sackarnd, Jan
Minnerup, Jens
Teismann, Inga
Ahring, Sigrid
Claus, Inga
Labeit, Bendix
Muhle, Paul
Suntrup-Krüger, Sonja
Warnecke, Tobias
Padberg, Jan-Sören
Dysphagia in Patients With Severe Coronavirus Disease 2019—Potential Neurologic Etiologies
title Dysphagia in Patients With Severe Coronavirus Disease 2019—Potential Neurologic Etiologies
title_full Dysphagia in Patients With Severe Coronavirus Disease 2019—Potential Neurologic Etiologies
title_fullStr Dysphagia in Patients With Severe Coronavirus Disease 2019—Potential Neurologic Etiologies
title_full_unstemmed Dysphagia in Patients With Severe Coronavirus Disease 2019—Potential Neurologic Etiologies
title_short Dysphagia in Patients With Severe Coronavirus Disease 2019—Potential Neurologic Etiologies
title_sort dysphagia in patients with severe coronavirus disease 2019—potential neurologic etiologies
topic Observational Study
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7837983/
https://www.ncbi.nlm.nih.gov/pubmed/33521647
http://dx.doi.org/10.1097/CCE.0000000000000332
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