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Tyrosine phosphatase SHP2 inhibitors in tumor-targeted therapies

Src homology containing protein tyrosine phosphatase 2 (SHP2) represents a noteworthy target for various diseases, serving as a well-known oncogenic phosphatase in cancers. As a result of the low cell permeability and poor bioavailability, the traditional inhibitors targeting the protein tyrosine ph...

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Detalles Bibliográficos
Autores principales:	Song, Zhendong, Wang, Meijing, Ge, Yang, Chen, Xue-Ping, Xu, Ziyang, Sun, Yang, Xiong, Xiao-Feng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7838030/ https://www.ncbi.nlm.nih.gov/pubmed/33532178 http://dx.doi.org/10.1016/j.apsb.2020.07.010

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