Dihydropyridine Calcium Channel Blockers Suppress the Transcription of PD-L1 by Inhibiting the Activation of STAT1

Programmed death ligand 1 (PD-L1) which is upregulated in various epithelial tumors, plays a central role in the evasion of the immune system. In addition to monoclonal antibodies that blocking PD1/PD-L1 axis, finding small molecule compounds that can suppress PD-L1 expression might be another subst...

Descripción completa

Detalles Bibliográficos
Autores principales: Pan, Xiaohui, Li, Run, Guo, Hongjie, Zhang, Wenxin, Xu, Xiaqing, Chen, Xi, Ding, Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7838064/
https://www.ncbi.nlm.nih.gov/pubmed/33519429
http://dx.doi.org/10.3389/fphar.2020.539261

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7838064/
https://www.ncbi.nlm.nih.gov/pubmed/33519429
http://dx.doi.org/10.3389/fphar.2020.539261

Ejemplares similares