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Dihydropyridine Calcium Channel Blockers Suppress the Transcription of PD-L1 by Inhibiting the Activation of STAT1

Programmed death ligand 1 (PD-L1) which is upregulated in various epithelial tumors, plays a central role in the evasion of the immune system. In addition to monoclonal antibodies that blocking PD1/PD-L1 axis, finding small molecule compounds that can suppress PD-L1 expression might be another subst...

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Detalles Bibliográficos
Autores principales:	Pan, Xiaohui, Li, Run, Guo, Hongjie, Zhang, Wenxin, Xu, Xiaqing, Chen, Xi, Ding, Ling
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7838064/ https://www.ncbi.nlm.nih.gov/pubmed/33519429 http://dx.doi.org/10.3389/fphar.2020.539261

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