Cargando…

Dl-3-n-Butylphthalide Alleviates Hippocampal Neuron Damage in Chronic Cerebral Hypoperfusion via Regulation of the CNTF/CNTFRα/JAK2/STAT3 Signaling Pathways

Chronic cerebral hypoperfusion (CCH) contributes to cognitive impairments, and hippocampal neuronal death is one of the key factors involved in this process. Dl-3-n-butylphthalide (D3NB) is a synthetic compound originally isolated from the seeds of Apium graveolens, which exhibits neuroprotective ef...

Descripción completa

Detalles Bibliográficos
Autores principales:	Li, Wenxian, Wei, Di, Zhu, Zheng, Xie, Xiaomei, Zhan, Shuqin, Zhang, Ru, Zhang, Guilian, Huang, Li’an
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7838126/ https://www.ncbi.nlm.nih.gov/pubmed/33519417 http://dx.doi.org/10.3389/fnagi.2020.587403

Ejemplares similares

Dl-3-n-Butylphthalide Reduces Cognitive Impairment Induced by Chronic Cerebral Hypoperfusion Through GDNF/GFRα1/Ret Signaling Preventing Hippocampal Neuron Apoptosis
por: Li, Wenxian, et al.
Publicado: (2019)

dl‐3‐n‐butylphthalide preserves white matter integrity and alleviates cognitive impairment in mice with chronic cerebral hypoperfusion
por: Han, Qin‐Yu, et al.
Publicado: (2019)

Dl-3-n-Butylphthalide Treatment Enhances Hemodynamics and Ameliorates Memory Deficits in Rats with Chronic Cerebral Hypoperfusion
por: Xiong, Zhilin, et al.
Publicado: (2017)

Dl-3-n-butylphthalide regulates cholinergic dysfunction in chronic cerebral hypoperfusion rats
por: Sun, Yanan, et al.
Publicado: (2020)

Effects of Dl-3-n-butylphthalide on cognitive functions and blood–brain barrier in chronic cerebral hypoperfusion rats
por: Ma, Yang, et al.
Publicado: (2023)

Activation of CNTF/CNTFRα Signaling Pathway by hRheb(S16H) Transduction of Dopaminergic Neurons In Vivo
por: Jeong, Kyoung Hoon, et al.
Publicado: (2015)

Correction to: Effects of Dl-3‑n‑butylphthalide on cognitive functions and blood–brain barrier in chronic cerebral hypoperfusion rats
por: Ma, Yang, et al.
Publicado: (2023)

Correction: Activation of CNTF/CNTFRα Signaling Pathway by hRheb(S16H) Transduction of Dopaminergic Neurons In Vivo
Publicado: (2015)

Dl-3-n-Butylphthalide Promotes Remyelination and Suppresses Inflammation by Regulating AMPK/SIRT1 and STAT3/NF-κB Signaling in Chronic Cerebral Hypoperfusion
por: Li, Meixi, et al.
Publicado: (2020)

The efficacy and safety of Dl-3n-butylphthalide on progressive cerebral infarction: A randomized controlled STROBE study
por: Zhang, Chenhao, et al.
Publicado: (2017)

DL-3-n-butylphthalide (NBP) alleviates poststroke cognitive impairment (PSCI) by suppressing neuroinflammation and oxidative stress
por: Zhang, Hui, et al.
Publicado: (2023)

Protective effects of dl-3n-butylphthalide against diffuse brain injury
por: Zhao, Yaning, et al.
Publicado: (2013)

Dl-3-n-Butylphthalide Reduces Cognitive Deficits and Alleviates Neuropathology in P301S Tau Transgenic Mice
por: Chang, Yanmin, et al.
Publicado: (2021)

DL-3-n-butylphthalide alleviates motor disturbance by suppressing ferroptosis in a rat model of Parkinson’s disease
por: Hu, Chun-Bo, et al.
Publicado: (2022)

DL-3-n-butylphthalide promotes hippocampal neurogenesis and reduces mossy fiber sprouting in chronic temporal lobe epilepsy rats
por: Zhao, Shanshan, et al.
Publicado: (2022)

Dl-3-n-Butylphthalide Alleviates Demyelination and Improves Cognitive Function by Promoting Mitochondrial Dynamics in White Matter Lesions
por: Feng, Yiwei, et al.
Publicado: (2021)

Corrigendum: Dl-3-n-Butylphthalide Reduces Cognitive Deficits and Alleviates Neuropathology in P301S Tau Transgenic Mice
por: Chang, Yanmin, et al.
Publicado: (2021)

Dl-3-n-Butylphthalide Exerts Dopaminergic Neuroprotection Through Inhibition of Neuroinflammation
por: Chen, Yajing, et al.
Publicado: (2019)

DL-3-n-butylphthalide improves cerebral hypoperfusion in patients with large cerebral atherosclerotic stenosis: a single-center, randomized, double-blind, placebo-controlled study
por: Chen, Dawei, et al.
Publicado: (2020)

Long-Term DL-3-n-Butylphthalide Treatment Alleviates Cognitive Impairment Correlate With Improving Synaptic Plasticity in SAMP8 Mice
por: Lv, Chaonan, et al.
Publicado: (2018)

Dl-3-n-Butylphthalide Ameliorates Diabetic Nephropathy by Ameliorating Excessive Fibrosis and Podocyte Apoptosis
por: Xu, Jingyu, et al.
Publicado: (2021)

Dl-3-n-butylphthalide Reduces Neurovascular Inflammation and Ischemic Brain Injury in Mice
por: Yang, Chun-Sheng, et al.
Publicado: (2019)

Corrigendum: Dl-3-n-Butylphthalide Exerts Dopaminergic Neuroprotection Through Inhibition of Neuroinflammation
por: Chen, Yajing, et al.
Publicado: (2021)

Dl-3-n-butylphthalide attenuates brain injury caused by cortical infarction accompanied by cranial venous drainage disturbance
por: Song, Kangping, et al.
Publicado: (2022)

Effects of Dl-3-n-butylphthalide on Cerebral Ischemia Infarction in Rat Model by Mass Spectrometry Imaging
por: Liu, Run-Zhe, et al.
Publicado: (2017)

Dl-3-n-butylphthalide inhibits neuroinflammation by stimulating foxp3 and Ki-67 in an ischemic stroke model
por: Liu, Xi, et al.
Publicado: (2021)

Dl-3-n-Butylphthalide Alleviates Behavioral and Cognitive Symptoms Via Modulating Mitochondrial Dynamics in the A53T-α-Synuclein Mouse Model of Parkinson’s Disease
por: Li, Huiying, et al.
Publicado: (2021)

Vascular protection and regenerative effects of intranasal DL-3-N-butylphthalide treatment after ischaemic stroke in mice
por: Qu, Mengyao, et al.
Publicado: (2020)

Dl-3-n-Butylphthalide promotes neovascularization and neurological recovery in a rat model of intracerebral hemorrhage
por: Tu, Ewen, et al.
Publicado: (2020)

DL-3-n-butylphthalide Increases Collateriogenesis and Functional Recovery after Focal Ischemic Stroke in Mice
por: Wei, Zheng Zachory, et al.
Publicado: (2021)

Dl‐3‐N‐butylphthalide promotes angiogenesis and upregulates sonic hedgehog expression after cerebral ischemia in rats
por: Zhou, Pan‐Ting, et al.
Publicado: (2019)

Efficacy and Safety of DL-3-n-Butylphthalide in the Treatment of Poststroke Cognitive Impairment: A Systematic Review and Meta-Analysis
por: Fan, Xueming, et al.
Publicado: (2022)

DL-3-n-butylphthalide improved physical and learning and memory performance of rodents exposed to acute and chronic hypobaric hypoxia
por: Xu, Gang, et al.
Publicado: (2021)

Neuronal STAT3 activation is essential for CNTF- and inflammatory stimulation-induced CNS axon regeneration
por: Leibinger, M, et al.
Publicado: (2013)

Dl-3-n-Butylphthalide Reduced Neuroinflammation by Inhibiting Inflammasome in Microglia in Mice after Middle Cerebral Artery Occlusion
por: Liu, Mengdi, et al.
Publicado: (2022)

DL-3n-Butylphthalide Improves Blood–Brain Barrier Integrity in Rat After Middle Cerebral Artery Occlusion
por: Mamtilahun, Muyassar, et al.
Publicado: (2021)

DL-3-N-Butylphthalide Promotes Cartilage Extracellular Matrix Synthesis and Inhibits Osteoarthritis Development by Regulating FoxO3a
por: Zhang, Yaxin, et al.
Publicado: (2022)

Effect of Dl-3-n-butylphthalide on mitochondrial Cox7c in models of cerebral ischemia/reperfusion injury
por: Jia, Jingjing, et al.
Publicado: (2023)

Dl-3-n-Butylphthalide Rescues Dopaminergic Neurons in Parkinson’s Disease Models by Inhibiting the NLRP3 Inflammasome and Ameliorating Mitochondrial Impairment
por: Que, Rongfang, et al.
Publicado: (2021)

clc is co-expressed with clf or cntfr in developing mouse muscles
por: de Bovis, Béatrice, et al.
Publicado: (2005)

Cannot write session to /tmp/vufind_sessions/sess_abbtbutd6v6mtllvrgec04ecsg