Natural podophyllotoxin analog 4DPG attenuates EMT and colorectal cancer progression via activation of checkpoint kinase 2

Epithelial–mesenchymal transition (EMT) is critical for the metastatic dissemination of cancer cells and contributes to drug resistance. In this study, we observed that epithelial colorectal cancer (CRC) cells transiently exposed to 5-fluorouracil (5-FU) (a chemotherapeutic drug for CRC) as well as...

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Detalles Bibliográficos
Autores principales: Katoch, Archana, Nayak, Debasis, Faheem, Mir Mohd., Kumar, Aviral, Sahu, Promod Kumar, Gupta, Ajai Prakash, Kumar, Lekha Dinesh, Goswami, Anindya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7838189/
https://www.ncbi.nlm.nih.gov/pubmed/33500399
http://dx.doi.org/10.1038/s41420-021-00405-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7838189/
https://www.ncbi.nlm.nih.gov/pubmed/33500399
http://dx.doi.org/10.1038/s41420-021-00405-3

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