Chronic BDNF simultaneously inhibits and unmasks superficial dorsal horn neuronal activity

Brain-derived neurotrophic factor (BDNF) is critically involved in the pathophysiology of chronic pain. However, the mechanisms of BDNF action on specific neuronal populations in the spinal superficial dorsal horn (SDH) requires further study. We used chronic BDNF treatment (200 ng/ml, 5–6 days) of...

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Detalles Bibliográficos
Autores principales: Alles, Sascha R. A., Odem, Max A., Lu, Van B., Cassidy, Ryan M., Smith, Peter A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7838274/
https://www.ncbi.nlm.nih.gov/pubmed/33500423
http://dx.doi.org/10.1038/s41598-021-81269-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7838274/
https://www.ncbi.nlm.nih.gov/pubmed/33500423
http://dx.doi.org/10.1038/s41598-021-81269-6

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