Metabolic regulation of telomere silencing by SESAME complex-catalyzed H3T11 phosphorylation

Telomeres are organized into a heterochromatin structure and maintenance of silent heterochromatin is required for chromosome stability. How telomere heterochromatin is dynamically regulated in response to stimuli remains unknown. Pyruvate kinase Pyk1 forms a complex named SESAME (Serine-responsive...

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Detalles Bibliográficos
Autores principales: Zhang, Shihao, Yu, Xilan, Zhang, Yuan, Xue, Xiangyan, Yu, Qi, Zha, Zitong, Gogol, Madelaine, Workman, Jerry L., Li, Shanshan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7838282/
https://www.ncbi.nlm.nih.gov/pubmed/33500413
http://dx.doi.org/10.1038/s41467-020-20711-1

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