Assessing the functional impact of PfRh5 genetic diversity on ex vivo erythrocyte invasion inhibition

The PfRh5-Basigin ligand–receptor interaction is an essential step in the merozoite invasion process and represents an attractive vaccine target. To reveal genotype–phenotype associations between naturally occurring allelic variants of PfRh5 and invasion inhibition, we performed ex vivo invasion inh...

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Detalles Bibliográficos
Autores principales: Moore, Adam J., Mangou, Khadidiatou, Diallo, Fatoumata, Sene, Seynabou D., Pouye, Mariama N., Sadio, Bacary D., Faye, Ousmane, Mbengue, Alassane, Bei, Amy K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7838290/
https://www.ncbi.nlm.nih.gov/pubmed/33500482
http://dx.doi.org/10.1038/s41598-021-81711-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7838290/
https://www.ncbi.nlm.nih.gov/pubmed/33500482
http://dx.doi.org/10.1038/s41598-021-81711-9

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