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Combined Use of Metformin and Everolimus Is Synergistic in the Treatment of Breast Cancer Cells

Everolimus inhibits mammalian target of rapamycin (mTOR) and leads to decreased protein synthesis and decreased cancer cell proliferation in many experimental systems. Adenosine 5′-monophosphate-activated protein kinase (AMPK) activators such as metformin have similar actions in keeping with the TSC...

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Detalles Bibliográficos
Autores principales:	Wang, Yunshan, Wei, Junmin, Li, Li, Fan, Cong, Sun, Ying
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cognizant Communication Corporation 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7838426/ https://www.ncbi.nlm.nih.gov/pubmed/26351208 http://dx.doi.org/10.3727/096504015X14348950540999

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