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Favorable postoperative outcomes for children with COVID-19 infection undergoing surgical intervention: Experience at a free-standing children's hospital

BACKGROUND: Current literature has shown that adult patients with perioperative Coronavirus Disease-2019 (COVID-19) have increased rates of postoperative morbidity and mortality. We hypothesized that children with COVID-19 have favorable postoperative outcomes compared to the reported adult experien...

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Autores principales: Mehl, Steven C., Loera, Jackquelin M., Shah, Sohail R., Vogel, Adam M., Fallon, Sara C., Glover, Chris D., Monson, Laura A., Enochs, Joyce A., Hollier, Larry H., Lopez, Monica E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7838581/
https://www.ncbi.nlm.nih.gov/pubmed/33581882
http://dx.doi.org/10.1016/j.jpedsurg.2021.01.033
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author Mehl, Steven C.
Loera, Jackquelin M.
Shah, Sohail R.
Vogel, Adam M.
Fallon, Sara C.
Glover, Chris D.
Monson, Laura A.
Enochs, Joyce A.
Hollier, Larry H.
Lopez, Monica E.
author_facet Mehl, Steven C.
Loera, Jackquelin M.
Shah, Sohail R.
Vogel, Adam M.
Fallon, Sara C.
Glover, Chris D.
Monson, Laura A.
Enochs, Joyce A.
Hollier, Larry H.
Lopez, Monica E.
author_sort Mehl, Steven C.
collection PubMed
description BACKGROUND: Current literature has shown that adult patients with perioperative Coronavirus Disease-2019 (COVID-19) have increased rates of postoperative morbidity and mortality. We hypothesized that children with COVID-19 have favorable postoperative outcomes compared to the reported adult experience. METHODS: We performed a retrospective cohort study for children with a confirmed preoperative COVID-19 diagnosis from April 1st, 2020 to August 15th, 2020 at a free-standing children's hospital. Primary outcomes evaluated were postoperative complications, readmissions, reoperations, and mortality within 30 days of operation. Secondary outcomes included hospital resource utilization, hospital length of stay, and postoperative oxygen support. RESULTS: A total of 66 children with preoperative confirmed COVID-19 were evaluated with median age of 9.5 years (interquartile range (IQR) 5–14) with 65% male and 70% Hispanic White. Sixty-five percent of patients had no comorbidities, with abdominal pain identified as the most common preoperative symptom (65%). Twenty-three percent of patients presented with no COVID-19 related symptoms. Eighty-two percent of patients had no preoperative chest imaging and 98% of patients did not receive preoperative oxygen support. General pediatric surgeons performed the majority of procedures (68%) with the most common diagnosis appendicitis (47%). Forty-one percent of patients were discharged the same day as surgery with 9% of patients utilizing postoperative intensive care unit resources and only 5% receiving postoperative invasive mechanical ventilation. Postoperative complications (7%), readmission (6%), and reoperation (6%) were infrequent, with no mortality. CONCLUSION: COVID-19+ children requiring surgery have a favorable postoperative course and short-term outcomes compared to the reported adult experience. TYPE OF STUDY: Prognosis Study. LEVEL OF EVIDENCE: Level IV.
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spelling pubmed-78385812021-01-27 Favorable postoperative outcomes for children with COVID-19 infection undergoing surgical intervention: Experience at a free-standing children's hospital Mehl, Steven C. Loera, Jackquelin M. Shah, Sohail R. Vogel, Adam M. Fallon, Sara C. Glover, Chris D. Monson, Laura A. Enochs, Joyce A. Hollier, Larry H. Lopez, Monica E. J Pediatr Surg Article BACKGROUND: Current literature has shown that adult patients with perioperative Coronavirus Disease-2019 (COVID-19) have increased rates of postoperative morbidity and mortality. We hypothesized that children with COVID-19 have favorable postoperative outcomes compared to the reported adult experience. METHODS: We performed a retrospective cohort study for children with a confirmed preoperative COVID-19 diagnosis from April 1st, 2020 to August 15th, 2020 at a free-standing children's hospital. Primary outcomes evaluated were postoperative complications, readmissions, reoperations, and mortality within 30 days of operation. Secondary outcomes included hospital resource utilization, hospital length of stay, and postoperative oxygen support. RESULTS: A total of 66 children with preoperative confirmed COVID-19 were evaluated with median age of 9.5 years (interquartile range (IQR) 5–14) with 65% male and 70% Hispanic White. Sixty-five percent of patients had no comorbidities, with abdominal pain identified as the most common preoperative symptom (65%). Twenty-three percent of patients presented with no COVID-19 related symptoms. Eighty-two percent of patients had no preoperative chest imaging and 98% of patients did not receive preoperative oxygen support. General pediatric surgeons performed the majority of procedures (68%) with the most common diagnosis appendicitis (47%). Forty-one percent of patients were discharged the same day as surgery with 9% of patients utilizing postoperative intensive care unit resources and only 5% receiving postoperative invasive mechanical ventilation. Postoperative complications (7%), readmission (6%), and reoperation (6%) were infrequent, with no mortality. CONCLUSION: COVID-19+ children requiring surgery have a favorable postoperative course and short-term outcomes compared to the reported adult experience. TYPE OF STUDY: Prognosis Study. LEVEL OF EVIDENCE: Level IV. Elsevier Inc. 2021-11 2021-01-27 /pmc/articles/PMC7838581/ /pubmed/33581882 http://dx.doi.org/10.1016/j.jpedsurg.2021.01.033 Text en © 2021 Elsevier Inc. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Mehl, Steven C.
Loera, Jackquelin M.
Shah, Sohail R.
Vogel, Adam M.
Fallon, Sara C.
Glover, Chris D.
Monson, Laura A.
Enochs, Joyce A.
Hollier, Larry H.
Lopez, Monica E.
Favorable postoperative outcomes for children with COVID-19 infection undergoing surgical intervention: Experience at a free-standing children's hospital
title Favorable postoperative outcomes for children with COVID-19 infection undergoing surgical intervention: Experience at a free-standing children's hospital
title_full Favorable postoperative outcomes for children with COVID-19 infection undergoing surgical intervention: Experience at a free-standing children's hospital
title_fullStr Favorable postoperative outcomes for children with COVID-19 infection undergoing surgical intervention: Experience at a free-standing children's hospital
title_full_unstemmed Favorable postoperative outcomes for children with COVID-19 infection undergoing surgical intervention: Experience at a free-standing children's hospital
title_short Favorable postoperative outcomes for children with COVID-19 infection undergoing surgical intervention: Experience at a free-standing children's hospital
title_sort favorable postoperative outcomes for children with covid-19 infection undergoing surgical intervention: experience at a free-standing children's hospital
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7838581/
https://www.ncbi.nlm.nih.gov/pubmed/33581882
http://dx.doi.org/10.1016/j.jpedsurg.2021.01.033
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