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Activation of p21 limits acute lung injury and induces early senescence after acid aspiration and mechanical ventilation
The p53/p21 pathway is activated in response to cell stress. However, its role in acute lung injury has not been elucidated. Acute lung injury is associated with disruption of the alveolo-capillary barrier leading to acute respiratory distress syndrome (ARDS). Mechanical ventilation may be necessary...
| Autores principales: | , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier Inc.
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7838583/ https://www.ncbi.nlm.nih.gov/pubmed/33515780 http://dx.doi.org/10.1016/j.trsl.2021.01.008 |