Cargando…

Non-viral Gene Therapy for Osteoarthritis

Strategies for delivering nucleic acids into damaged and diseased tissues have been divided into two major areas: viral and non-viral gene therapy. In this mini-review article we discuss the application of gene therapy for the treatment of osteoarthritis (OA), one of the most common forms of arthrit...

Descripción completa

Detalles Bibliográficos
Autores principales:	Uzieliene, Ilona, Kalvaityte, Ursule, Bernotiene, Eiva, Mobasheri, Ali
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Bioengineering and Biotechnology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7838585/ https://www.ncbi.nlm.nih.gov/pubmed/33520968 http://dx.doi.org/10.3389/fbioe.2020.618399

Ejemplares similares

Emerging Technologies and Platforms for the Immunodetection of Multiple Biochemical Markers in Osteoarthritis Research and Therapy
por: Bernotiene, Eiva, et al.
Publicado: (2020)

Exploring the translational potential of clusterin as a biomarker of early osteoarthritis
por: Kalvaityte, Ursule, et al.
Publicado: (2021)

Cardiovascular Drugs and Osteoarthritis: Effects of Targeting Ion Channels
por: Vaiciuleviciute, Raminta, et al.
Publicado: (2021)

The Role of Physical Stimuli on Calcium Channels in Chondrogenic Differentiation of Mesenchymal Stem Cells
por: Uzieliene, Ilona, et al.
Publicado: (2018)

Evaluation of Cartilage Integrity Following Administration of Oral and Intraarticular Nifedipine in a Murine Model of Osteoarthritis
por: Aleksiuk, Viktorija, et al.
Publicado: (2023)

Nanotechnological Strategies for Osteoarthritis Diagnosis, Monitoring, Clinical Management, and Regenerative Medicine: Recent Advances and Future Opportunities
por: Mohammadinejad, Reza, et al.
Publicado: (2020)

The Effect of CaV1.2 Inhibitor Nifedipine on Chondrogenic Differentiation of Human Bone Marrow or Menstrual Blood-Derived Mesenchymal Stem Cells and Chondrocytes
por: Uzieliene, Ilona, et al.
Publicado: (2023)

The Antihypertensive Drug Nifedipine Modulates the Metabolism of Chondrocytes and Human Bone Marrow-Derived Mesenchymal Stem Cells
por: Uzieliene, Ilona, et al.
Publicado: (2019)

Mechanotransducive Biomimetic Systems for Chondrogenic Differentiation In Vitro
por: Uzieliene, Ilona, et al.
Publicado: (2021)

Different phenotypes and chondrogenic responses of human menstrual blood and bone marrow mesenchymal stem cells to activin A and TGF-β3
por: Uzieliene, Ilona, et al.
Publicado: (2021)

Editorial: Non-viral vectors for gene therapy/nucleic acid delivery
por: Poddar, Arpita, et al.
Publicado: (2023)

Menstrual Blood-Derived Stem Cell Paracrine Factors Possess Stimulatory Effects on Chondrogenesis In Vitro and Diminish the Degradation of Articular Cartilage during Osteoarthritis
por: Uzieliene, Ilona, et al.
Publicado: (2023)

Electrical Stimulation in Cartilage Tissue Engineering
por: Vaiciuleviciute, Raminta, et al.
Publicado: (2023)

At the Intersection of Biomaterials and Gene Therapy: Progress in Non-viral Delivery of Nucleic Acids
por: Uludag, Hasan, et al.
Publicado: (2019)

A White Paper on Collagen Hydrolyzates and Ultrahydrolyzates: Potential Supplements to Support Joint Health in Osteoarthritis?
por: Mobasheri, Ali, et al.
Publicado: (2021)

Non-viral Gene Delivery Methods for Bone and Joints
por: Gantenbein, Benjamin, et al.
Publicado: (2020)

Mesenchymal Stem Cell Therapy for Osteoarthritis: The Critical Role of the Cell Secretome
por: Mancuso, Patrizio, et al.
Publicado: (2019)

Editorial: Nanomaterials for the diagnosis and therapy of viral infections
por: Bardi, Giuseppe, et al.
Publicado: (2023)

Chondroitin Sulfate-Tyramine-Based Hydrogels for Cartilage Tissue Repair
por: Uzieliene, Ilona, et al.
Publicado: (2023)

The Effects of Mechanical Load on Chondrogenic Responses of Bone Marrow Mesenchymal Stem Cells and Chondrocytes Encapsulated in Chondroitin Sulfate-Based Hydrogel
por: Uzieliene, Ilona, et al.
Publicado: (2023)

Is low-level laser therapy effective for patients with knee joint osteoarthritis? implications and strategies to promote laser therapy usage
por: Khumaidi, Mohammad Adib, et al.
Publicado: (2022)

Manufacturing of non-viral protein nanocages for biotechnological and biomedical applications
por: João, Jorge, et al.
Publicado: (2023)

Stimulation of Chondrocyte and Bone Marrow Mesenchymal Stem Cell Chondrogenic Response by Polypyrrole and Polypyrrole/Gold Nanoparticles
por: Uzieliene, Ilona, et al.
Publicado: (2023)

Modeling the Impact of Meniscal Tears on von Mises Stress of Knee Cartilage Tissue
por: Ardatov, Oleg, et al.
Publicado: (2023)

Adipokine Signaling Pathways in Osteoarthritis
por: Zhang, Chaofan, et al.
Publicado: (2022)

Hydrogels for Treatment of Different Degrees of Osteoarthritis
por: Wang, Shuze, et al.
Publicado: (2022)

Investigation of Cancer Cell Migration and Proliferation on Synthetic Extracellular Matrix Peptide Hydrogels
por: Balion, Zbigniev, et al.
Publicado: (2020)

The Potential of Menstrual Blood-Derived Mesenchymal Stem Cells for Cartilage Repair and Regeneration: Novel Aspects
por: Uzieliene, I., et al.
Publicado: (2018)

Characterization and Chondroprotective Effects of Extracellular Vesicles From Plasma- and Serum-Based Autologous Blood-Derived Products for Osteoarthritis Therapy
por: Otahal, Alexander, et al.
Publicado: (2020)

Transfer learning-assisted 3D deep learning models for knee osteoarthritis detection: Data from the osteoarthritis initiative
por: Yeoh, Pauline Shan Qing, et al.
Publicado: (2023)

The potential therapeutic role of extracellular vesicles in osteoarthritis
por: Zhuang, Yu, et al.
Publicado: (2022)

Gene Expression Signatures of Synovial Fluid Multipotent Stromal Cells in Advanced Knee Osteoarthritis and Following Knee Joint Distraction
por: Sanjurjo-Rodriguez, Clara, et al.
Publicado: (2020)

Interplay of Inflammatory Mediators with Epigenetics and Cartilage Modifications in Osteoarthritis
por: Raman, Swarna, et al.
Publicado: (2018)

Immunomodulation of MSCs and MSC-Derived Extracellular Vesicles in Osteoarthritis
por: Zhao, Xige, et al.
Publicado: (2020)

Editorial: Post-Traumatic Osteoarthritis After Meniscus Injury
por: Patel, Jay M., et al.
Publicado: (2022)

Cartilage organoids and osteoarthritis research: a narrative review
por: Zeng, Daofu, et al.
Publicado: (2023)

Non-viral Gene Delivery of Interleukin-1 Receptor Antagonist Using Collagen-Hydroxyapatite Scaffold Protects Rat BM-MSCs From IL-1β-Mediated Inhibition of Osteogenesis
por: Lackington, William A., et al.
Publicado: (2020)

GEL-MAN Hydrogel Loaded With Triamcinolone Acetonide for the Treatment of Osteoarthritis
por: Chen, Kai, et al.
Publicado: (2020)

Harnessing hyaluronic acid for the treatment of osteoarthritis: A bibliometric analysis
por: Zhang, Jun, et al.
Publicado: (2022)

Gene Therapy for Bone Engineering
por: Balmayor, Elizabeth Rosado, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_4dabbiokrrfiqk86no9a971j9u