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Anexelekto (AXL) Increases Resistance to EGFR-TKI and Activation of AKT and ERK1/2 in Non-Small Cell Lung Cancer Cells
Recently, epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs) have revolutionized non-small cell lung cancer (NSCLC) treatment. However, resistance remains a major obstacle. Anexelekto (AXL) is a member of receptor tyrosine kinases (RTKs) and shares the same downstream signaling...
Autores principales: | Tian, Yaqiong, Zhang, Zengli, Miao, Liyun, Yang, Zhimin, Yang, Jie, Wang, Yinhua, Qian, Danwen, Cai, Hourong, Wang, Yongsheng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cognizant Communication Corporation
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7838623/ https://www.ncbi.nlm.nih.gov/pubmed/27712586 http://dx.doi.org/10.3727/096504016X14648701447814 |
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