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Radiosensitization of Non-Small Cell Lung Cancer Cells by Inhibition of TGF-β1 Signaling With SB431542 Is Dependent on p53 Status

Although medically inoperable patients with stage I non-small cell lung cancer cells (NSCLC) are often treated with stereotactic body radiation therapy, its efficacy can be compromised due to poor radiosensitivity of cancer cells. Inhibition of transforming growth factor-β1 (TGF-β1) using LY364947 a...

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Detalles Bibliográficos
Autores principales: Zhao, Yifan, Wang, Longxiao, Huang, Qianyi, Jiang, Youqin, Wang, Jingdong, Zhang, Liyuan, Tian, Ye, Yang, Hongying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cognizant Communication Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7838670/
https://www.ncbi.nlm.nih.gov/pubmed/27178816
http://dx.doi.org/10.3727/096504016X14570992647087