Ritonavir Interacts With Belinostat to Cause Endoplasmic Reticulum Stress and Histone Acetylation in Renal Cancer Cells

The histone deacetylase (HDAC) inhibitor belinostat increases the amount of unfolded proteins in cells by promoting the acetylation of heat shock protein 90 (HSP90), thereby disrupting its chaperone function. The human immunodeficiency virus protease inhibitor ritonavir, on the other hand, not only...

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Detalles Bibliográficos
Autores principales: Isono, Makoto, Sato, Akinori, Okubo, Kazuki, Asano, Takako, Asano, Tomohiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cognizant Communication Corporation 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7838685/
https://www.ncbi.nlm.nih.gov/pubmed/27712589
http://dx.doi.org/10.3727/096504016X14666990347635

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7838685/
https://www.ncbi.nlm.nih.gov/pubmed/27712589
http://dx.doi.org/10.3727/096504016X14666990347635

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