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Knockdown of HVEM, a Lymphocyte Regulator Gene, in Ovarian Cancer Cells Increases Sensitivity to Activated T Cells

Ovarian cancer is highly malignant with a gradually increasing incidence and a high mortality rate. Immunosuppression is induced in ovarian cancer, although the mechanism detail is not clear. It has been indicated that HVEM (herpesvirus entry mediator) B- and T-lymphocyte attenuator (BTLA) negativel...

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Detalles Bibliográficos
Autores principales: Zhang, Ting, Ye, Lei, Han, Lingfei, He, Qizhi, Zhu, Jianlong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cognizant Communication Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7838697/
https://www.ncbi.nlm.nih.gov/pubmed/27458100
http://dx.doi.org/10.3727/096504016X14641336229602