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Enhancement of Drug Sensitivity by Knockdown of HIF-1α in Gastric Carcinoma Cells

In this study, the effects of hypoxia-inducible factor-1α (HIF-1α) on gastric carcinoma (GC) drug resistance through apoptosis-related genes are investigated. First, HIF-1α-specific siRNA was synthetized and transfected into drug-resistant GC cell line OCUM-2MD3/L-OHP. Then MTT assay was applied to...

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Detalles Bibliográficos
Autores principales:	Zhao, Qun, Tan, Bi-Bo, Li, Yong, Fan, Li-Qiao, Yang, Pei-Gang, Tian, Yuan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cognizant Communication Corporation 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7838699/ https://www.ncbi.nlm.nih.gov/pubmed/26931435 http://dx.doi.org/10.3727/096504015X14500513118029

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