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Risk-Based Decision Making: A Systematic Scoping Review of Animal Models and a Pilot Study on the Effects of Sleep Deprivation in Rats
Animals, including humans, frequently make decisions involving risk or uncertainty. Different strategies in these decisions can be advantageous depending the circumstances. Short sleep duration seems to be associated with more risky decisions in humans. Animal models for risk-based decision making c...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7838799/ https://www.ncbi.nlm.nih.gov/pubmed/33498259 http://dx.doi.org/10.3390/clockssleep3010003 |
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author | Leenaars, Cathalijn H.C. Van der Mierden, Stevie Joosten, Ruud N.J.M.A. Van der Weide, Marnix A. Schirris, Mischa Dematteis, Maurice Meijboom, Franck L.B. Feenstra, Matthijs G.P. Bleich, André |
author_facet | Leenaars, Cathalijn H.C. Van der Mierden, Stevie Joosten, Ruud N.J.M.A. Van der Weide, Marnix A. Schirris, Mischa Dematteis, Maurice Meijboom, Franck L.B. Feenstra, Matthijs G.P. Bleich, André |
author_sort | Leenaars, Cathalijn H.C. |
collection | PubMed |
description | Animals, including humans, frequently make decisions involving risk or uncertainty. Different strategies in these decisions can be advantageous depending the circumstances. Short sleep duration seems to be associated with more risky decisions in humans. Animal models for risk-based decision making can increase mechanistic understanding, but very little data is available concerning the effects of sleep. We combined primary- and meta-research to explore the relationship between sleep and risk-based decision making in animals. Our first objective was to create an overview of the available animal models for risky decision making. We performed a systematic scoping review. Our searches in Pubmed and Psychinfo retrieved 712 references, of which 235 were included. Animal models for risk-based decision making have been described for rodents, non-human primates, birds, pigs and honey-bees. We discuss task designs and model validity. Our second objective was to apply this knowledge and perform a pilot study on the effect of sleep deprivation. We trained and tested male Wistar rats on a probability discounting task; a “safe” lever always resulted in 1 reward, a “risky” lever resulted in 4 or no rewards. Rats adapted their preferences to variations in reward probabilities (p < 0.001), but 12 h of sleep deprivation during the light phase did not clearly alter risk preference (p = 0.21). |
format | Online Article Text |
id | pubmed-7838799 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-78387992021-01-28 Risk-Based Decision Making: A Systematic Scoping Review of Animal Models and a Pilot Study on the Effects of Sleep Deprivation in Rats Leenaars, Cathalijn H.C. Van der Mierden, Stevie Joosten, Ruud N.J.M.A. Van der Weide, Marnix A. Schirris, Mischa Dematteis, Maurice Meijboom, Franck L.B. Feenstra, Matthijs G.P. Bleich, André Clocks Sleep Article Animals, including humans, frequently make decisions involving risk or uncertainty. Different strategies in these decisions can be advantageous depending the circumstances. Short sleep duration seems to be associated with more risky decisions in humans. Animal models for risk-based decision making can increase mechanistic understanding, but very little data is available concerning the effects of sleep. We combined primary- and meta-research to explore the relationship between sleep and risk-based decision making in animals. Our first objective was to create an overview of the available animal models for risky decision making. We performed a systematic scoping review. Our searches in Pubmed and Psychinfo retrieved 712 references, of which 235 were included. Animal models for risk-based decision making have been described for rodents, non-human primates, birds, pigs and honey-bees. We discuss task designs and model validity. Our second objective was to apply this knowledge and perform a pilot study on the effect of sleep deprivation. We trained and tested male Wistar rats on a probability discounting task; a “safe” lever always resulted in 1 reward, a “risky” lever resulted in 4 or no rewards. Rats adapted their preferences to variations in reward probabilities (p < 0.001), but 12 h of sleep deprivation during the light phase did not clearly alter risk preference (p = 0.21). MDPI 2021-01-20 /pmc/articles/PMC7838799/ /pubmed/33498259 http://dx.doi.org/10.3390/clockssleep3010003 Text en © 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Leenaars, Cathalijn H.C. Van der Mierden, Stevie Joosten, Ruud N.J.M.A. Van der Weide, Marnix A. Schirris, Mischa Dematteis, Maurice Meijboom, Franck L.B. Feenstra, Matthijs G.P. Bleich, André Risk-Based Decision Making: A Systematic Scoping Review of Animal Models and a Pilot Study on the Effects of Sleep Deprivation in Rats |
title | Risk-Based Decision Making: A Systematic Scoping Review of Animal Models and a Pilot Study on the Effects of Sleep Deprivation in Rats |
title_full | Risk-Based Decision Making: A Systematic Scoping Review of Animal Models and a Pilot Study on the Effects of Sleep Deprivation in Rats |
title_fullStr | Risk-Based Decision Making: A Systematic Scoping Review of Animal Models and a Pilot Study on the Effects of Sleep Deprivation in Rats |
title_full_unstemmed | Risk-Based Decision Making: A Systematic Scoping Review of Animal Models and a Pilot Study on the Effects of Sleep Deprivation in Rats |
title_short | Risk-Based Decision Making: A Systematic Scoping Review of Animal Models and a Pilot Study on the Effects of Sleep Deprivation in Rats |
title_sort | risk-based decision making: a systematic scoping review of animal models and a pilot study on the effects of sleep deprivation in rats |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7838799/ https://www.ncbi.nlm.nih.gov/pubmed/33498259 http://dx.doi.org/10.3390/clockssleep3010003 |
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