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Risk-Based Decision Making: A Systematic Scoping Review of Animal Models and a Pilot Study on the Effects of Sleep Deprivation in Rats

Animals, including humans, frequently make decisions involving risk or uncertainty. Different strategies in these decisions can be advantageous depending the circumstances. Short sleep duration seems to be associated with more risky decisions in humans. Animal models for risk-based decision making c...

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Autores principales: Leenaars, Cathalijn H.C., Van der Mierden, Stevie, Joosten, Ruud N.J.M.A., Van der Weide, Marnix A., Schirris, Mischa, Dematteis, Maurice, Meijboom, Franck L.B., Feenstra, Matthijs G.P., Bleich, André
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7838799/
https://www.ncbi.nlm.nih.gov/pubmed/33498259
http://dx.doi.org/10.3390/clockssleep3010003
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author Leenaars, Cathalijn H.C.
Van der Mierden, Stevie
Joosten, Ruud N.J.M.A.
Van der Weide, Marnix A.
Schirris, Mischa
Dematteis, Maurice
Meijboom, Franck L.B.
Feenstra, Matthijs G.P.
Bleich, André
author_facet Leenaars, Cathalijn H.C.
Van der Mierden, Stevie
Joosten, Ruud N.J.M.A.
Van der Weide, Marnix A.
Schirris, Mischa
Dematteis, Maurice
Meijboom, Franck L.B.
Feenstra, Matthijs G.P.
Bleich, André
author_sort Leenaars, Cathalijn H.C.
collection PubMed
description Animals, including humans, frequently make decisions involving risk or uncertainty. Different strategies in these decisions can be advantageous depending the circumstances. Short sleep duration seems to be associated with more risky decisions in humans. Animal models for risk-based decision making can increase mechanistic understanding, but very little data is available concerning the effects of sleep. We combined primary- and meta-research to explore the relationship between sleep and risk-based decision making in animals. Our first objective was to create an overview of the available animal models for risky decision making. We performed a systematic scoping review. Our searches in Pubmed and Psychinfo retrieved 712 references, of which 235 were included. Animal models for risk-based decision making have been described for rodents, non-human primates, birds, pigs and honey-bees. We discuss task designs and model validity. Our second objective was to apply this knowledge and perform a pilot study on the effect of sleep deprivation. We trained and tested male Wistar rats on a probability discounting task; a “safe” lever always resulted in 1 reward, a “risky” lever resulted in 4 or no rewards. Rats adapted their preferences to variations in reward probabilities (p < 0.001), but 12 h of sleep deprivation during the light phase did not clearly alter risk preference (p = 0.21).
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spelling pubmed-78387992021-01-28 Risk-Based Decision Making: A Systematic Scoping Review of Animal Models and a Pilot Study on the Effects of Sleep Deprivation in Rats Leenaars, Cathalijn H.C. Van der Mierden, Stevie Joosten, Ruud N.J.M.A. Van der Weide, Marnix A. Schirris, Mischa Dematteis, Maurice Meijboom, Franck L.B. Feenstra, Matthijs G.P. Bleich, André Clocks Sleep Article Animals, including humans, frequently make decisions involving risk or uncertainty. Different strategies in these decisions can be advantageous depending the circumstances. Short sleep duration seems to be associated with more risky decisions in humans. Animal models for risk-based decision making can increase mechanistic understanding, but very little data is available concerning the effects of sleep. We combined primary- and meta-research to explore the relationship between sleep and risk-based decision making in animals. Our first objective was to create an overview of the available animal models for risky decision making. We performed a systematic scoping review. Our searches in Pubmed and Psychinfo retrieved 712 references, of which 235 were included. Animal models for risk-based decision making have been described for rodents, non-human primates, birds, pigs and honey-bees. We discuss task designs and model validity. Our second objective was to apply this knowledge and perform a pilot study on the effect of sleep deprivation. We trained and tested male Wistar rats on a probability discounting task; a “safe” lever always resulted in 1 reward, a “risky” lever resulted in 4 or no rewards. Rats adapted their preferences to variations in reward probabilities (p < 0.001), but 12 h of sleep deprivation during the light phase did not clearly alter risk preference (p = 0.21). MDPI 2021-01-20 /pmc/articles/PMC7838799/ /pubmed/33498259 http://dx.doi.org/10.3390/clockssleep3010003 Text en © 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Leenaars, Cathalijn H.C.
Van der Mierden, Stevie
Joosten, Ruud N.J.M.A.
Van der Weide, Marnix A.
Schirris, Mischa
Dematteis, Maurice
Meijboom, Franck L.B.
Feenstra, Matthijs G.P.
Bleich, André
Risk-Based Decision Making: A Systematic Scoping Review of Animal Models and a Pilot Study on the Effects of Sleep Deprivation in Rats
title Risk-Based Decision Making: A Systematic Scoping Review of Animal Models and a Pilot Study on the Effects of Sleep Deprivation in Rats
title_full Risk-Based Decision Making: A Systematic Scoping Review of Animal Models and a Pilot Study on the Effects of Sleep Deprivation in Rats
title_fullStr Risk-Based Decision Making: A Systematic Scoping Review of Animal Models and a Pilot Study on the Effects of Sleep Deprivation in Rats
title_full_unstemmed Risk-Based Decision Making: A Systematic Scoping Review of Animal Models and a Pilot Study on the Effects of Sleep Deprivation in Rats
title_short Risk-Based Decision Making: A Systematic Scoping Review of Animal Models and a Pilot Study on the Effects of Sleep Deprivation in Rats
title_sort risk-based decision making: a systematic scoping review of animal models and a pilot study on the effects of sleep deprivation in rats
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7838799/
https://www.ncbi.nlm.nih.gov/pubmed/33498259
http://dx.doi.org/10.3390/clockssleep3010003
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