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Effective treatment with Tocilizumab in a COVID-19 patient on maintenance hemodialysis: A case report

Coronavirus disease 2019 (COVID-19) is a rapidly spreading infective disease caused by the severe acute respiratory syndrome coronavirus 2 virus (SARS-CoV-2). The management of this disease remains a challenge particularly in certain subgroups of patients such in hemodialysis patients who have highe...

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Autores principales: Nourié, Nicole, Chamaa, Mohamed Ammar, Mouawad, Sarah, Kotait, Micheline Mia, Finianos, Serge, Azar, Hiba, Chelala, Dania
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7838846/
https://www.ncbi.nlm.nih.gov/pubmed/33502716
http://dx.doi.org/10.1007/s13730-021-00577-y
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author Nourié, Nicole
Chamaa, Mohamed Ammar
Mouawad, Sarah
Kotait, Micheline Mia
Finianos, Serge
Azar, Hiba
Chelala, Dania
author_facet Nourié, Nicole
Chamaa, Mohamed Ammar
Mouawad, Sarah
Kotait, Micheline Mia
Finianos, Serge
Azar, Hiba
Chelala, Dania
author_sort Nourié, Nicole
collection PubMed
description Coronavirus disease 2019 (COVID-19) is a rapidly spreading infective disease caused by the severe acute respiratory syndrome coronavirus 2 virus (SARS-CoV-2). The management of this disease remains a challenge particularly in certain subgroups of patients such in hemodialysis patients who have higher exposure rates due to the nature of their in-hospital care, and higher mortality due to their burden of comorbidities. We report a case of a 52-year-old patient with Von Hippel Lindau syndrome and end-stage renal disease on hemodialysis who contracted COVID-19 infection. Despite the patient’s rapidly deteriorating clinical status he was successfully treated with Tocilizumab, after which he showed rapid improvement in his clinical, biological and radiological parameters. Although few studies were available regarding the use of Tocilizumab in the dialysis population, its use proved to be effective and well tolerated in our patient.
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spelling pubmed-78388462021-01-28 Effective treatment with Tocilizumab in a COVID-19 patient on maintenance hemodialysis: A case report Nourié, Nicole Chamaa, Mohamed Ammar Mouawad, Sarah Kotait, Micheline Mia Finianos, Serge Azar, Hiba Chelala, Dania CEN Case Rep Case Report Coronavirus disease 2019 (COVID-19) is a rapidly spreading infective disease caused by the severe acute respiratory syndrome coronavirus 2 virus (SARS-CoV-2). The management of this disease remains a challenge particularly in certain subgroups of patients such in hemodialysis patients who have higher exposure rates due to the nature of their in-hospital care, and higher mortality due to their burden of comorbidities. We report a case of a 52-year-old patient with Von Hippel Lindau syndrome and end-stage renal disease on hemodialysis who contracted COVID-19 infection. Despite the patient’s rapidly deteriorating clinical status he was successfully treated with Tocilizumab, after which he showed rapid improvement in his clinical, biological and radiological parameters. Although few studies were available regarding the use of Tocilizumab in the dialysis population, its use proved to be effective and well tolerated in our patient. Springer Singapore 2021-01-27 /pmc/articles/PMC7838846/ /pubmed/33502716 http://dx.doi.org/10.1007/s13730-021-00577-y Text en © Japanese Society of Nephrology 2021
spellingShingle Case Report
Nourié, Nicole
Chamaa, Mohamed Ammar
Mouawad, Sarah
Kotait, Micheline Mia
Finianos, Serge
Azar, Hiba
Chelala, Dania
Effective treatment with Tocilizumab in a COVID-19 patient on maintenance hemodialysis: A case report
title Effective treatment with Tocilizumab in a COVID-19 patient on maintenance hemodialysis: A case report
title_full Effective treatment with Tocilizumab in a COVID-19 patient on maintenance hemodialysis: A case report
title_fullStr Effective treatment with Tocilizumab in a COVID-19 patient on maintenance hemodialysis: A case report
title_full_unstemmed Effective treatment with Tocilizumab in a COVID-19 patient on maintenance hemodialysis: A case report
title_short Effective treatment with Tocilizumab in a COVID-19 patient on maintenance hemodialysis: A case report
title_sort effective treatment with tocilizumab in a covid-19 patient on maintenance hemodialysis: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7838846/
https://www.ncbi.nlm.nih.gov/pubmed/33502716
http://dx.doi.org/10.1007/s13730-021-00577-y
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