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A Comparative Study of Corneal Topography in Children with Autism Spectrum Disorder: A Cross-Sectional Study
Purpose: To investigate the corneal characteristics in individuals with autism spectrum disorder (ASD) and age-matched typical development (TD) participants. Methods: This cross-sectional, clinically based study compared children with ASD to age-matched TD participants. Corneal topography was measur...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7838863/ https://www.ncbi.nlm.nih.gov/pubmed/33467505 http://dx.doi.org/10.3390/vision5010004 |
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author | ALGarzaie, Maha A. Alsaqr, Ali M. |
author_facet | ALGarzaie, Maha A. Alsaqr, Ali M. |
author_sort | ALGarzaie, Maha A. |
collection | PubMed |
description | Purpose: To investigate the corneal characteristics in individuals with autism spectrum disorder (ASD) and age-matched typical development (TD) participants. Methods: This cross-sectional, clinically based study compared children with ASD to age-matched TD participants. Corneal topography was measured with a portable EyeSys Vista system. The distance visual acuity (VA) and the contrast sensitivity (CS) were determined. The refractive error (RE) was assessed using a 2WIN autorefractometer. Results: A total of 31 children with ASD (mean age: 12.78 ± 4.49 years), and 60 participants with TD (mean age: 13.65 ± 3.56 years) were recruited. The two groups were similar in age (t = −2.084, p = 0.075) and VA (t = −0.35, p = 0.32). Most of the children with ASD had a significant amount of refractive errors (REs; range: +5.25 to −5.50 DS), and astigmatism was dominant (range: −0.25 to −4.50 DC). There was no statistically significant difference between both groups in terms of average corneal power (t = 1.12, p = 0.39). The children with ASD and participants with TD also did not differ significantly in terms of corneal shape descriptors (p > 0.05), such as corneal asphericity, inferior superior index, opposite sector index, and differential sector index. The spherical equivalent did not differ significantly between the ASD participants and participants with TD (t = 1.15, p = 0.15). There was a significant difference (p < 0.05) in the astigmatism component between the ASD participants and the participants with TD. |
format | Online Article Text |
id | pubmed-7838863 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-78388632021-01-28 A Comparative Study of Corneal Topography in Children with Autism Spectrum Disorder: A Cross-Sectional Study ALGarzaie, Maha A. Alsaqr, Ali M. Vision (Basel) Article Purpose: To investigate the corneal characteristics in individuals with autism spectrum disorder (ASD) and age-matched typical development (TD) participants. Methods: This cross-sectional, clinically based study compared children with ASD to age-matched TD participants. Corneal topography was measured with a portable EyeSys Vista system. The distance visual acuity (VA) and the contrast sensitivity (CS) were determined. The refractive error (RE) was assessed using a 2WIN autorefractometer. Results: A total of 31 children with ASD (mean age: 12.78 ± 4.49 years), and 60 participants with TD (mean age: 13.65 ± 3.56 years) were recruited. The two groups were similar in age (t = −2.084, p = 0.075) and VA (t = −0.35, p = 0.32). Most of the children with ASD had a significant amount of refractive errors (REs; range: +5.25 to −5.50 DS), and astigmatism was dominant (range: −0.25 to −4.50 DC). There was no statistically significant difference between both groups in terms of average corneal power (t = 1.12, p = 0.39). The children with ASD and participants with TD also did not differ significantly in terms of corneal shape descriptors (p > 0.05), such as corneal asphericity, inferior superior index, opposite sector index, and differential sector index. The spherical equivalent did not differ significantly between the ASD participants and participants with TD (t = 1.15, p = 0.15). There was a significant difference (p < 0.05) in the astigmatism component between the ASD participants and the participants with TD. MDPI 2021-01-15 /pmc/articles/PMC7838863/ /pubmed/33467505 http://dx.doi.org/10.3390/vision5010004 Text en © 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article ALGarzaie, Maha A. Alsaqr, Ali M. A Comparative Study of Corneal Topography in Children with Autism Spectrum Disorder: A Cross-Sectional Study |
title | A Comparative Study of Corneal Topography in Children with Autism Spectrum Disorder: A Cross-Sectional Study |
title_full | A Comparative Study of Corneal Topography in Children with Autism Spectrum Disorder: A Cross-Sectional Study |
title_fullStr | A Comparative Study of Corneal Topography in Children with Autism Spectrum Disorder: A Cross-Sectional Study |
title_full_unstemmed | A Comparative Study of Corneal Topography in Children with Autism Spectrum Disorder: A Cross-Sectional Study |
title_short | A Comparative Study of Corneal Topography in Children with Autism Spectrum Disorder: A Cross-Sectional Study |
title_sort | comparative study of corneal topography in children with autism spectrum disorder: a cross-sectional study |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7838863/ https://www.ncbi.nlm.nih.gov/pubmed/33467505 http://dx.doi.org/10.3390/vision5010004 |
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