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Pathogenic Pore Forming Proteins of Plasmodium Triggers the Necrosis of Endothelial Cells Attributed to Malaria Severity

Severe malaria caused by Plasmodium falciparum poses a major global health problem with high morbidity and mortality. P. falciparum harbors a family of pore-forming proteins (PFPs), known as perforin like proteins (PLPs), which are structurally equivalent to prokaryotic PFPs. These PLPs are secreted...

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Detalles Bibliográficos
Autores principales: Shivappagowdar, Abhishek, Garg, Swati, Srivastava, Akriti, Hada, Rahul S., Kalia, Inderjeet, Singh, Agam P., Garg, Lalit C., Pati, Soumya, Singh, Shailja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7839052/
https://www.ncbi.nlm.nih.gov/pubmed/33467515
http://dx.doi.org/10.3390/toxins13010062