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Pathogenic Pore Forming Proteins of Plasmodium Triggers the Necrosis of Endothelial Cells Attributed to Malaria Severity
Severe malaria caused by Plasmodium falciparum poses a major global health problem with high morbidity and mortality. P. falciparum harbors a family of pore-forming proteins (PFPs), known as perforin like proteins (PLPs), which are structurally equivalent to prokaryotic PFPs. These PLPs are secreted...
Autores principales: | Shivappagowdar, Abhishek, Garg, Swati, Srivastava, Akriti, Hada, Rahul S., Kalia, Inderjeet, Singh, Agam P., Garg, Lalit C., Pati, Soumya, Singh, Shailja |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7839052/ https://www.ncbi.nlm.nih.gov/pubmed/33467515 http://dx.doi.org/10.3390/toxins13010062 |
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